Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22916955 | 0.93 | BRD4 (0.49) | ALDH1A1KDM4ETP53HPGDHSD17B10 | |
| SCHEMBL23174922 | 0.90 | BRD4 (0.44) | ALDH1A1KDM4ETP53HPGDHSD17B10 | |
| SCHEMBL25514682 | 0.89 | BRD4 (0.41) | ALDH1A1KDM4ETP53HPGDHSD17B10 | |
| SCHEMBL21423951 | 0.89 | ALDH1A1 (0.47) | ALDH1A1KDM4ETP53HPGDHSD17B10 | |
| SCHEMBL30094313 | 0.87 | TDP1 (0.40) | ALDH1A1KDM4ETP53HPGDHSD17B10 | |
| SCHEMBL21423952 | 0.84 | L3MBTL1 (0.57) | ALDH1A1KDM4ETP53HPGDHSD17B10 | |
| SCHEMBL25213878 | 0.84 | BRD4 (0.37) | ALDH1A1KDM4ETP53HSD17B10BRD4 | |
| SCHEMBL22917038 | 0.81 | BRD4 (0.52) | ALDH1A1KDM4ETP53HPGDHSD17B10 | |
| SCHEMBL25514686 | 0.78 | BRD4 (0.43) | ALDH1A1KDM4ETP53HPGDHSD17B10 | |
| SCHEMBL21413199 | 0.77 | BRD4 (0.45) | ALDH1A1KDM4ETP53HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019189778-A1 | COMPOUND WITH ANTICANCER ACTIVITY | 協和発酵キリン株式会社 | 2019-10-03 | — | — | WO | disclosed |