Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | SETDB1 | Q15047 | 5/20 | 0.39 |
| ▸ | MIF | P14174 | 5/20 | 0.35 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16579400 | 0.78 | NOTUM (0.52) | NOTUMNPSR1ALOX15SETDB1MIF | |
| SCHEMBL23011639 | 0.77 | NOTUM (0.51) | NOTUMNPSR1ALOX15SETDB1MIF | |
| SCHEMBL19662980 | 0.75 | NOTUM (0.50) | NOTUMNPSR1ALOX15GBA1 | |
| SCHEMBL24556741 | 0.75 | NOTUM (0.50) | NOTUMNPSR1ALOX15SETDB1MIF | |
| SCHEMBL25882774 | 0.75 | NOTUM (0.47) | NOTUMNPSR1ALOX15MALT1GBA1 | |
| SCHEMBL25884344 | 0.74 | NOTUM (0.49) | NOTUMNPSR1ALOX15GBA1 | |
| SCHEMBL22906161 | 0.74 | NOTUM (0.49) | NOTUMNPSR1ALOX15SETDB1 | |
| SCHEMBL7963203 | 0.74 | NOTUM (0.49) | NOTUMNPSR1ALOX15 | |
| SCHEMBL26318734 | 0.74 | NOTUM (0.46) | NOTUMNPSR1ALOX15SETDB1 | |
| SCHEMBL22429826 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3778573-A1 | COMPOUND WITH ANTICANCER ACTIVITY | Kyowa Kirin Co., Ltd. (JP) | 2021-02-17 | — | — | EP | disclosed |
| WO-2019189778-A1 | COMPOUND WITH ANTICANCER ACTIVITY | 協和発酵キリン株式会社 | 2019-10-03 | — | — | WO | disclosed |