Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | SETDB1 | Q15047 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22906161 | 0.77 | NOTUM (0.49) | NOTUMNPSR1ALOX15SETDB1 | |
| SCHEMBL24256389 | 0.75 | NOTUM (0.47) | NOTUMNPSR1ALOX15 | |
| SCHEMBL16579400 | 0.74 | NOTUM (0.52) | NOTUMNPSR1ALOX15SETDB1 | |
| SCHEMBL25884344 | 0.74 | NOTUM (0.49) | NOTUMNPSR1ALOX15 | |
| SCHEMBL21423974 | 0.74 | NOTUM (0.49) | NOTUMNPSR1ALOX15SETDB1 | |
| SCHEMBL23011639 | 0.73 | NOTUM (0.51) | NOTUMNPSR1ALOX15SETDB1 | |
| SCHEMBL24556741 | 0.72 | NOTUM (0.50) | NOTUMNPSR1ALOX15SETDB1 | |
| SCHEMBL19662980 | 0.72 | NOTUM (0.50) | NOTUMNPSR1ALOX15 | |
| SCHEMBL26401475 | 0.71 | ADRB2 (0.42) | NOTUM | |
| SCHEMBL7963203 | 0.71 | NOTUM (0.49) | NOTUMNPSR1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230293701-A1 | LIGAND COMPOUNDS, CONJUGATES, AND APPLICATIONS THEREOF | ARGORNA PHARMACEUTICALS CO., LTD. (CN) | 2023-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230293701-A1 | LIGAND COMPOUNDS, CONJUGATES, AND APPLICATIONS THEREOF | ASGR1, HAVCR2, SLC10A1 | NOTUM 2792/4885NPSR1 215/4885ALOX15 3226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.