Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | PREP | P48147 | 1/20 | 0.36 |
| ▸ | FAP | Q12884 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | ECE1 | P42892 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.34 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.34 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25514706 | 0.91 | ALDH1A1 (0.44) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL5597209 | 0.83 | KDM4E (0.48) | ALDH1A1SOAT1DPP4PREPFAP | |
| SCHEMBL25964962 | 0.79 | ALDH1A1 (0.45) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL20991917 | 0.79 | TDP1 (0.41) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL28497156 | 0.79 | ALDH1A1 (0.40) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL10199485 | 0.78 | ALDH1A1 (0.43) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL14015909 | 0.77 | ALDH1A1 (0.39) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL10311745 | 0.76 | MAPK1 (0.50) | ALDH1A1MAPTKDM4EMAPK1HIF1A | |
| SCHEMBL14069651 | 0.76 | KDM4E (0.39) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL2608304 | 0.74 | ALDH1A1 (0.40) | ALDH1A1LMNAMAPTPTGS2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3778573-A1 | COMPOUND WITH ANTICANCER ACTIVITY | Kyowa Kirin Co., Ltd. (JP) | 2021-02-17 | — | — | EP | disclosed |
| WO-2019189778-A1 | COMPOUND WITH ANTICANCER ACTIVITY | 協和発酵キリン株式会社 | 2019-10-03 | — | — | WO | disclosed |