SCHEMBL2143173

SCHEMBL2143173

Cc1ccc(O)cc1S(=O)(=O)N=C=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.44
ALDH1A1 P00352 4/20 0.44
PKM P14618 1/20 0.44
TSHR P16473 1/20 0.40
GLO1 Q04760 3/20 0.39
PTGS1 P23219 1/20 0.37
ATM Q13315 2/20 0.35
ESR2 Q92731 2/20 0.35
MEN1 O00255 1/20 0.35
ESR1 P03372 1/20 0.35
KMT2A Q03164 1/20 0.35
ACHE P22303 1/20 0.35
GFER P55789 2/20 0.35
LMNA P02545 1/20 0.35
HPGD P15428 1/20 0.35
HIF1A Q16665 1/20 0.35
HSD17B10 Q99714 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
POLB P06746 2/20 0.34
RAPGEF4 Q8WZA2 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5654777 0.82 TDP1 (0.42) GAAALDH1A1TSHRMEN1KMT2A
SCHEMBL5654372 0.81 LMNA (0.43) ALDH1A1TSHRLMNAHPGDSMN1; SMN2
SCHEMBL5657224 0.78 CYP3A4 (0.54) ALDH1A1TSHRGLO1LMNAHPGD
SCHEMBL29693002 0.74 KMT2A (0.43) GAAALDH1A1TSHRESR2MEN1
SCHEMBL395353 0.74 KMT2A (0.43) GAAALDH1A1TSHRESR2MEN1
SCHEMBL7760538 0.74 PTGS1 (0.60) GAAALDH1A1PKMTSHRPTGS1
SCHEMBL121153 0.74 LMNA (0.53) GAAALDH1A1PKMTSHRPTGS1
SCHEMBL9811626 0.73 ALDH1A1 (0.47) GAAALDH1A1PKMTSHRPTGS1
SCHEMBL9340792 0.73 ALDH1A1 (0.56) GAAALDH1A1PKMLMNASMN1; SMN2
SCHEMBL2141529 0.72 ALDH1A1 (0.43) GAAALDH1A1ATMESR2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170107330-A1 SULFUR-BASED POLYMERS CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2017-04-20 US disclosed
EP-3097137-A1 SULFUR-BASED POLYMERS Construction Research & Technology GmbH (DE) 2016-11-30 EP disclosed
US-9133363-B2 Stabilized urethane based surface coating BLUM HOLGER (CH) 2015-09-15 US disclosed
WO-2015107002-A1 SULFUR-BASED POLYMERS CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2015-07-23 WO disclosed
EP-2896644-A1 SULFUR-BASED POLYMERS Construction Research & Technology GmbH (DE) 2015-07-22 EP disclosed
US-20150011690-A1 STABILIZED URETHANE BASED SURFACE COATING BLUM HOLGER (CH) 2015-01-08 US disclosed
EP-2686358-B1 STABILIZED URETHANE BASED SURFACE COATING BLUM HOLGER (CH) 2014-11-19 EP disclosed
EP-2686358-A1 STABILIZED URETHANE BASED SURFACE COATING Blum, Holger (CH) 2014-01-22 EP disclosed
WO-2013139388-A1 STABILIZED URETHANE BASED SURFACE COATING BLUM HOLGER (CH) 2013-09-26 WO disclosed
US-8343303-B2 Composition useful as an adhesive for installing vehicle windows DOW GLOBAL TECHNOLOGIES LLC (US) 2013-01-01 US disclosed
US-20110048610-A1 COMPOSITION USEFUL AS AN ADHESIVE FOR INSTALLING VEHICLE WINDOWS DOW GLOBAL TECHNOLOGIES INC. 2011-03-03 US disclosed
US-7892395-B2 Composition useful as an adhesive for installing vehicle windows DOW GLOBAL TECHNOLOGIES INC. (US) 2011-02-22 US disclosed
EP-2097465-B1 COMPOSITION USEFUL AS AN ADHESIVE FOR INSTALLING VEHICLE WINDOWS DOW GLOBAL TECHNOLOGIES INC (US) 2010-11-03 EP disclosed
US-20080149257-A1 Composition useful as an adhesive for installing vehicle windows THE DOW CHEMICAL COMPANY 2008-06-26 US disclosed
US-7148279-B2 Golf ball compositions comprising dynamically vulcanized blends of highly neutralized polymers and diene rubber ACUSHNET COMPANY (US) 2006-12-12 US disclosed
US-20040242802-A1 Golf ball compositions comprising dynamically vulcanized blends of highly neutralized polymers and diene rubber JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-12-02 US disclosed
US-5421876-A Solvent-free, organoclay-filled asphaltic polyurethane dispersion and method of making and using it TREMCO, INC. (US) 1995-06-06 US disclosed
US-5338786-A Storage stability; containing a thiophene compounds and an arylsulphoryisocyanate compound CHEMICAL INVESTMENTS, LTD. (GB) 1994-08-16 US disclosed