SCHEMBL2143293

SCHEMBL2143293

O=C(CCCCCCC/C=C\CCCCCCCCCC(O)CO)OCCO

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.58
MGLL Q99685 1/20 0.54
FAAH O00519 4/20 0.49
EPHX2 P34913 1/20 0.46
PRKCE Q02156 1/20 0.46
PRKCQ Q04759 1/20 0.46
PRKCD Q05655 1/20 0.46
PRKCA P17252 1/20 0.46
KDM4E B2RXH2 1/20 0.44
DUSP3 P51452 1/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
LMNA P02545 1/20 0.44
LPAR1 Q92633 5/20 0.43
CES2 O00748 1/20 0.43
ENPP2 Q13822 1/20 0.43
LPAR4 Q99677 1/20 0.43
LPAR5 Q9H1C0 1/20 0.43
LPAR2 Q9HBW0 1/20 0.43
LPAR3 Q9UBY5 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5136440 0.91 KDM4E (0.51) DGKAMGLLPRKCEPRKCQPRKCD
SCHEMBL28074566 0.87 DGKA (0.76) DGKAFAAHPRKCEPRKCQPRKCD
SCHEMBL1313190 0.87 DGKA (0.76) DGKAFAAHPRKCEPRKCQPRKCD
SCHEMBL20678200 0.85 DGKA (0.61) DGKAMGLLFAAHEPHX2PRKCE
SCHEMBL27513328 0.84 FFAR1 (0.66) DGKAMGLLFAAHEPHX2PRKCE
SCHEMBL142809 0.84 FFAR1 (0.66) DGKAMGLLFAAHEPHX2PRKCE
SCHEMBL1462396 0.84 DGKA (0.57) DGKAMGLLFAAHEPHX2PRKCE
Alcohol SCHEMBL28345960 0.83 DGKA (0.80) DGKAFAAHPRKCEPRKCQPRKCD
Glycerin SCHEMBL5701746 0.79 DGKA (0.65) DGKAMGLLFAAHPRKCEPRKCQ
SCHEMBL25354733 0.79 DGKA (0.78) DGKAFAAHPRKCEPRKCQPRKCD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7863478-B2 1,3-Bis-[3-(4-methoxyphenyl)-2-propenoyloxy]-2-oxopropane; novel alpha-hydroxyketone derivatives as light-protection filters for cosmetic or drug products; used in cosmetic protective coatings; solar radiation; sunscreen agents; aging resistance; wrinkle resistance; food additives; dermatology MERCK PATENT GMBH (DE) 2011-01-04 US disclosed
US-20060014019-A1 Non-flak coated colouring pigment and method for the production and use thereof KUEBELBECK ARMIN 2006-01-19 US disclosed