Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.57 |
| ▸ | MGLL | Q99685 | 1/20 | 0.53 |
| ▸ | FAAH | O00519 | 2/20 | 0.49 |
| ▸ | LPAR1 | Q92633 | 7/20 | 0.47 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.47 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.47 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.46 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.46 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.46 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.46 |
| ▸ | PRKCA | P17252 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1462388 | 0.93 | KDM4E (0.51) | DGKAMGLLLPAR1LPAR4LPAR2 | |
| SCHEMBL8685383 | 0.91 | DGKA (0.53) | DGKAMGLLFAAHLPAR1LPAR4 | |
| SCHEMBL7128696 | 0.89 | MGLL (0.65) | DGKAMGLLFAAHLPAR1LPAR4 | |
| SCHEMBL1899102 | 0.86 | KDM4E (0.52) | DGKAMGLLFAAHLPAR1LPAR4 | |
| SCHEMBL1487853 | 0.85 | KDM4E (0.55) | DGKAMGLLFAAHLPAR1LPAR4 | |
| SCHEMBL2143293 | 0.84 | DGKA (0.58) | DGKAMGLLFAAHLPAR1LPAR4 | |
| SCHEMBL2905900 | 0.81 | MGLL (0.62) | DGKAMGLLFAAHLPAR1LPAR4 | |
| SCHEMBL16829781 | 0.80 | MGLL (0.57) | DGKAMGLLFAAHLPAR1LPAR4 | |
| SCHEMBL16829780 | 0.80 | MGLL (0.57) | DGKAMGLLFAAHLPAR1LPAR4 | |
| SCHEMBL16829784 | 0.80 | MGLL (0.57) | DGKAMGLLFAAHLPAR1LPAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110152201-A1 | EMULSION PRECONCENTRATES CONTAINING CYCLOSPORIN OR A MACROLIDE | AMBUEHL MICHAEL | 2011-06-23 | — | — | US | disclosed |
| US-20110086071-A1 | Pharmaceutical Compositions Comprising Terbinafine | BONNY JEAN-DANIEL | 2011-04-14 | — | — | US | disclosed |
| US-20110071186-A1 | ORGANIC COMPOUNDS | WONG MICHELLE PIK-HAN | 2011-03-24 | — | — | US | disclosed |