Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | ACACA | Q13085 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21432804 | 0.90 | DRD2 (0.38) | EPHX1DRD2JAK2JAK1SIRT2 | |
| SCHEMBL21419083 | 0.89 | EPHX1 (0.40) | EPHX1DRD2JAK2JAK1SIRT2 | |
| SCHEMBL21432996 | 0.88 | EPHX1 (0.39) | EPHX1DRD2JAK2JAK1SIRT2 | |
| SCHEMBL1567661 | 0.85 | EPHX1 (0.41) | EPHX1DRD2JAK2JAK1SIRT2 | |
| SCHEMBL21419114 | 0.81 | JAK2 (0.38) | EPHX1DRD2JAK2JAK1SIRT2 | |
| SCHEMBL21419084 | 0.81 | EPHX1 (0.43) | EPHX1DRD2JAK2JAK1SIRT2 | |
| SCHEMBL21432992 | 0.78 | DRD2 (0.45) | DRD2ALDH1A1GFER | |
| SCHEMBL15724297 | 0.77 | KDM4E (0.33) | ALDH1A1 | |
| SCHEMBL21419079 | 0.76 | EPHX1 (0.41) | EPHX1DRD2JAK2JAK1OPRM1 | |
| SCHEMBL21432422 | 0.75 | FPR3 (0.35) | EPHX1DRD2JAK2JAK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019191667-A1 | IMIDAZOPIPERAZINE INHIBITORS OF TRANSCRIPTION ACTIVATING PROTEINS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2019-10-03 | — | — | WO | disclosed |