Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.39 |
| ▸ | RECQL | P46063 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29430086 | 0.86 | TDP1 (0.53) | APPEPHX1GAAHIF1ATDP1 | |
| SCHEMBL28241555 | 0.86 | TDP1 (0.53) | APPEPHX1GAAHIF1ATDP1 | |
| Hydrochloric Acid SCHEMBL10340416 | 0.85 | KDM4E (0.55) | APPEPHX1GAAHIF1ATDP1 | |
| SCHEMBL1064971 | 0.75 | EPHX1 (0.60) | APPEPHX1GAAHIF1ATDP1 | |
| SCHEMBL11651790 | 0.74 | TRPA1 (0.64) | ALDH1A1GAAHIF1AALOX12HTT | |
| SCHEMBL15451317 | 0.74 | EPHX1 (0.50) | APPEPHX1ALDH1A1GAAHIF1A | |
| SCHEMBL11742573 | 0.74 | APP (0.57) | APPALDH1A1HIF1AKDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL15663072 | 0.74 | EPHX1 (0.58) | APPEPHX1GAAHIF1ATDP1 | |
| SCHEMBL5673527 | 0.73 | APP (0.53) | APPEPHX1ALDH1A1HTTLMNA | |
| SCHEMBL30002874 | 0.73 | APP (0.53) | APPEPHX1ALDH1A1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190309289-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. | 2019-10-10 | — | — | US | disclosed |