Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.42 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2143453 | 1.00 | TSHR (0.50) | TSHRCYP1A2PDPK1MAPTLMNA | |
| SCHEMBL25611633 | 0.80 | CYP1A2 (0.45) | CYP1A2MAPTLMNAPLIN1RECQL | |
| SCHEMBL20972782 | 0.79 | CYP1A2 (0.44) | CYP1A2LMNAACHEALDH1A1HPGD | |
| SCHEMBL20972780 | 0.79 | CYP1A2 (0.44) | CYP1A2LMNAACHEALDH1A1HPGD | |
| SCHEMBL31353019 | 0.79 | TSHR (0.50) | TSHRCYP1A2MAPTLMNAPLIN1 | |
| SCHEMBL29110171 | 0.76 | TSHR (0.47) | TSHRCYP1A2MAPTLMNAPLIN1 | |
| SCHEMBL29110168 | 0.76 | TSHR (0.47) | TSHRCYP1A2MAPTLMNAPLIN1 | |
| SCHEMBL909932 | 0.71 | TSHR (0.41) | TSHRCYP1A2MAPTLMNAPLIN1 | |
| SCHEMBL28804616 | 0.71 | TSHR (0.41) | TSHRCYP1A2MAPTLMNAPLIN1 | |
| SCHEMBL17767257 | 0.71 | KMT2A (0.50) | TSHRMAPTBCHETNFRSF1AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2258477-B1 | CATALYST AND MICHAEL ADDITION REACTION PROCESS | JAPAN SCIENCE & TECH AGENCY (JP) | 2015-03-25 | — | — | EP | disclosed |
| US-8222177-B2 | Catalyst and reaction process | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2012-07-17 | — | — | US | disclosed |
| US-20110054190-A1 | CATALYST AND REACTION PROCESS | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2011-03-03 | — | — | US | disclosed |
| EP-2258477-A1 | CATALYST AND REACTION PROCESS | Japan Science and Technology Agency (JP) | 2010-12-08 | — | — | EP | disclosed |
| WO-2009096409-A1 | CATALYST AND REACTION PROCESS | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2009-08-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110054190-A1 | CATALYST AND REACTION PROCESS | ME1, MAL2, ME2 | TSHR 2185/4885CYP1A2 28/4885PDPK1 4324/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.