Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 2/20 | 0.55 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10737114 | 0.83 | LSS (0.57) | LSSSRD5A2GAAMAPTMAOB | |
| SCHEMBL9361185 | 0.82 | LSS (0.62) | LSSSRD5A2GAAMAPTMAOB | |
| SCHEMBL10740990 | 0.82 | LSS (0.62) | LSSSRD5A2GAAMAPTMAOB | |
| SCHEMBL21439587 | 0.81 | PPARA (0.47) | GAAMAPTMAOBLMNAL3MBTL1 | |
| SCHEMBL5817865 | 0.81 | MAPK1 (0.62) | LSSSRD5A2GAAMAPTLMNA | |
| SCHEMBL16561598 | 0.80 | GAA (0.54) | SRD5A2GAAMAPTMAOBLMNA | |
| SCHEMBL38644 | 0.80 | SRD5A2 (0.60) | LSSSRD5A2GAAMAPTMAOB | |
| SCHEMBL21439460 | 0.78 | MAOB (0.44) | GAAMAPTMAOBLMNAL3MBTL1 | |
| SCHEMBL9365160 | 0.77 | LSS (0.73) | LSSGAAMAPTCRHBPCRHR2 | |
| SCHEMBL24000908 | 0.77 | PKM (0.61) | L3MBTL1POLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3774738-A1 | INDENE DERIVATIVES USEFUL IN TREATING PAIN AND INFLAMMATION | Aquinox Pharmaceuticals (Canada) Inc. (CA) | 2021-02-17 | — | — | EP | disclosed |
| WO-2019195777-A1 | INDENE DERIVATIVES USEFUL IN TREATING PAIN AND INFLAMMATION | AQUINOX PHARMACEUTICALS (CANADA) INC. (CA) | 2019-10-10 | — | — | WO | disclosed |