Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.42 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21439460 | 0.84 | MAOB (0.44) | PPARAMAOBGAAL3MBTL1PSMB1 | |
| SCHEMBL16561598 | 0.84 | GAA (0.54) | PPARAMAOBGAAL3MBTL1PSMB1 | |
| SCHEMBL31747364 | 0.83 | PARP10 (0.60) | MAOBL3MBTL1PARP10PRSS1 | |
| SCHEMBL21439344 | 0.81 | LSS (0.55) | MAOBGAAL3MBTL1LMNAMAPT | |
| SCHEMBL24000908 | 0.81 | PKM (0.61) | L3MBTL1TSHRTP53 | |
| SCHEMBL12804425 | 0.79 | CLK1 (0.49) | PPARAMAOBGAAL3MBTL1LMNA | |
| SCHEMBL8170794 | 0.78 | TDP1 (0.50) | MAOBGAAL3MBTL1CYP3A4TSHR | |
| SCHEMBL5385295 | 0.78 | GAA (0.66) | PPARAGAAL3MBTL1LMNAPARP10 | |
| SCHEMBL11592057 | 0.78 | L3MBTL1 (0.58) | GAAL3MBTL1LMNACYP1A2CYP3A4 | |
| SCHEMBL5811176 | 0.78 | GAA (0.70) | PPARAGAAL3MBTL1LMNAPARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3774738-A1 | INDENE DERIVATIVES USEFUL IN TREATING PAIN AND INFLAMMATION | Aquinox Pharmaceuticals (Canada) Inc. (CA) | 2021-02-17 | — | — | EP | disclosed |
| WO-2019195777-A1 | INDENE DERIVATIVES USEFUL IN TREATING PAIN AND INFLAMMATION | AQUINOX PHARMACEUTICALS (CANADA) INC. (CA) | 2019-10-10 | — | — | WO | disclosed |