Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.52 |
| ▸ | ITGAV | P06756 | 3/20 | 0.52 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.52 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.52 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.51 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.50 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.49 |
| ▸ | MC4R | P32245 | 9/20 | 0.49 |
| ▸ | MC5R | P33032 | 9/20 | 0.49 |
| ▸ | MC3R | P41968 | 9/20 | 0.49 |
| ▸ | MC1R | Q01726 | 9/20 | 0.49 |
| ▸ | CTSG | P08311 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15308349 | 0.96 | ITGB3 (0.53) | ITGB3ITGAVITGB1ITGA5CXCR4 | |
| SCHEMBL16152202 | 0.92 | ITGB3 (0.55) | ITGB3ITGAVITGB1ITGA5ITGA2B | |
| SCHEMBL21440744 | 0.91 | ITGB3 (0.51) | ITGB3ITGAVITGB1ITGA5CXCR4 | |
| SCHEMBL24285405 | 0.91 | ITGB3 (0.53) | ITGB3ITGAVITGB1ITGA5CXCR4 | |
| SCHEMBL18132947 | 0.91 | ITGB3 (0.53) | ITGB3ITGAVITGB1ITGA5CXCR4 | |
| SCHEMBL17612703 | 0.91 | MC4R (0.56) | ITGB3ITGAVITGA2BITGB5CACNA1B | |
| SCHEMBL29393726 | 0.90 | ITGB3 (0.59) | ITGB3ITGAVCXCR4ITGA2BITGB5 | |
| SCHEMBL23823920 | 0.90 | CACNA1B (0.53) | ITGB3ITGAVITGB1ITGA5ITGA2B | |
| SCHEMBL15397366 | 0.89 | ITGB3 (0.60) | ITGB3ITGAVITGB1ITGA5ITGA2B | |
| SCHEMBL10138534 | 0.89 | ITGB3 (0.60) | ITGB3ITGAVITGB1ITGA5ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10434197-B2 | Tetrazine-trans-cyclooctene ligation for the rapid construction of radionuclide labeled probes | UNIVERSITY OF DELAWARE (US) | 2019-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10434197-B2 | Tetrazine-trans-cyclooctene ligation for the rapid construction of radionuclide labeled probes | TTL, TALDO1, TTI1 | ITGB3 2868/4885ITGAV 2907/4885ITGB1 2056/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.