SCHEMBL21440818

SCHEMBL21440818

CNCCCOCCOCCOCCNC(=O)COCC(C)=O

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 4/20 0.39
▸ RECQL P46063 1/20 0.39
▸ CES2 O00748 1/20 0.39
▸ MEN1 O00255 1/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ ALDH1A1 P00352 2/20 0.36
▸ CASP1 P29466 1/20 0.35
▸ CASP7 P55210 1/20 0.35
▸ HSD17B10 Q99714 1/20 0.35
▸ FAAH O00519 1/20 0.34
▸ TLR2 O60603 1/20 0.34
▸ GLP1R P43220 5/20 0.32
▸ SLC9A3 P48764 1/20 0.32
▸ SMN1; SMN2 Q16637 1/20 0.32
▸ NPSR1 Q6W5P4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13034763 0.95 TSHR (0.43) TSHRRECQLCES2MEN1KMT2A
SCHEMBL13040233 0.92 MEN1 (0.41) TSHRRECQLCES2MEN1KMT2A
SCHEMBL13034764 0.92 MEN1 (0.41) TSHRRECQLCES2MEN1KMT2A
SCHEMBL7006602 0.92 MEN1 (0.41) TSHRRECQLCES2MEN1KMT2A
SCHEMBL21242622 0.91 CES2 (0.42) TSHRRECQLCES2MEN1KMT2A
SCHEMBL21242896 0.91 CES2 (0.42) TSHRRECQLCES2MEN1KMT2A
SCHEMBL21242696 0.91 CES2 (0.42) TSHRRECQLCES2MEN1KMT2A
SCHEMBL12641023 0.89 MEN1 (0.41) TSHRRECQLCES2MEN1KMT2A
SCHEMBL19544555 0.89 MEN1 (0.41) TSHRRECQLCES2MEN1KMT2A
SCHEMBL21440826 0.89 MEN1 (0.41) TSHRRECQLCES2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230143604-A1 QW DOSING OF GIP RECEPTOR AGONIST PEPTIDE COMPOUNDS AND USES THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2023-05-11 — — US disclosed
US-20220135638-A1 GIP RECEPTOR AGONIST PEPTIDE COMPOUNDS AND USES THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2022-05-05 — — US disclosed
US-20220016215-A1 GIP RECEPTOR AGONIST PEPTIDE COMPOUNDS AND USES THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2022-01-20 — — US disclosed
US-11174301-B2 Peptide compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2021-11-16 — — US disclosed
US-20200140505-A1 PEPTIDE COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMTED (JP) 2020-05-07 — — US disclosed
US-10435445-B2 Peptide compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2019-10-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200140505-A1 PEPTIDE COMPOUND GIPR, GLP1R, GRPR TSHR 57/4885RECQL 4569/4885CES2 4494/4885
US-20220016215-A1 GIP RECEPTOR AGONIST PEPTIDE COMPOUNDS AND USES THEREOF GIPR, GLP1R, GRPR TSHR 66/4885RECQL 3151/4885CES2 4794/4885
US-20230143604-A1 QW DOSING OF GIP RECEPTOR AGONIST PEPTIDE COMPOUNDS AND USES THEREOF GIPR, GLP1R, GRPR TSHR 84/4885RECQL 2595/4885CES2 4566/4885
US-11174301-B2 Peptide compound GIPR, GLP1R, GRPR TSHR 57/4885RECQL 4569/4885CES2 4494/4885
US-10435445-B2 Peptide compound GIPR, GLP1R, GRPR TSHR 64/4885RECQL 4552/4885CES2 4534/4885
US-20220135638-A1 GIP RECEPTOR AGONIST PEPTIDE COMPOUNDS AND USES THEREOF GIPR, GLP1R, VIPR1 TSHR 69/4885RECQL 3665/4885CES2 3756/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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