SCHEMBL21440833

SCHEMBL21440833

CN[C@@H](CCC(=O)N[C@H](CCC(C)=O)C(=O)O)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ NOD1 Q9Y239 9/20 0.53
▸ FOLH1 Q04609 5/20 0.44
▸ NAALAD2 Q9Y3Q0 2/20 0.44
▸ RIMKLA Q8IXN7 1/20 0.44
▸ GNPAT O15228 1/20 0.42
▸ FNTA P49354 2/20 0.38
▸ FNTB P49356 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12118226 1.00 NOD1 (0.53) NOD1FOLH1NAALAD2RIMKLAGNPAT
SCHEMBL21440846 1.00 NOD1 (0.53) NOD1FOLH1NAALAD2RIMKLAGNPAT
SCHEMBL13377667 1.00 NOD1 (0.53) NOD1FOLH1NAALAD2RIMKLAGNPAT
SCHEMBL21242989 1.00 NOD1 (0.53) NOD1FOLH1NAALAD2RIMKLAGNPAT
SCHEMBL21242721 1.00 NOD1 (0.53) NOD1FOLH1NAALAD2RIMKLAGNPAT
SCHEMBL23875397 0.89 FOLH1 (0.47) NOD1FOLH1NAALAD2RIMKLAGNPAT
SCHEMBL12118214 0.89 FOLH1 (0.43) NOD1FOLH1NAALAD2RIMKLAFNTA
SCHEMBL22111315 0.89 FOLH1 (0.43) NOD1FOLH1NAALAD2RIMKLAFNTA
SCHEMBL71800 0.89 FOLH1 (0.43) NOD1FOLH1NAALAD2RIMKLAFNTA
SCHEMBL14478725 0.87 NOD1 (0.54) NOD1FOLH1NAALAD2RIMKLAGNPAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230143604-A1 QW DOSING OF GIP RECEPTOR AGONIST PEPTIDE COMPOUNDS AND USES THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2023-05-11 — — US disclosed
US-20220135638-A1 GIP RECEPTOR AGONIST PEPTIDE COMPOUNDS AND USES THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2022-05-05 — — US disclosed
US-20220016215-A1 GIP RECEPTOR AGONIST PEPTIDE COMPOUNDS AND USES THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2022-01-20 — — US disclosed
US-11174301-B2 Peptide compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2021-11-16 — — US disclosed
US-20200140505-A1 PEPTIDE COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMTED (JP) 2020-05-07 — — US disclosed
US-10435445-B2 Peptide compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2019-10-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200140505-A1 PEPTIDE COMPOUND GIPR, GLP1R, GRPR NOD1 2042/4885FOLH1 566/4885NAALAD2 1096/4885
US-20220016215-A1 GIP RECEPTOR AGONIST PEPTIDE COMPOUNDS AND USES THEREOF GIPR, GLP1R, GRPR NOD1 3126/4885FOLH1 1327/4885NAALAD2 3255/4885
US-20230143604-A1 QW DOSING OF GIP RECEPTOR AGONIST PEPTIDE COMPOUNDS AND USES THEREOF GIPR, GLP1R, GRPR NOD1 2186/4885FOLH1 736/4885NAALAD2 1789/4885
US-11174301-B2 Peptide compound GIPR, GLP1R, GRPR NOD1 2042/4885FOLH1 566/4885NAALAD2 1096/4885
US-10435445-B2 Peptide compound GIPR, GLP1R, GRPR NOD1 1825/4885FOLH1 551/4885NAALAD2 1192/4885
US-20220135638-A1 GIP RECEPTOR AGONIST PEPTIDE COMPOUNDS AND USES THEREOF GIPR, GLP1R, VIPR1 NOD1 1471/4885FOLH1 1590/4885NAALAD2 2478/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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