SCHEMBL71800

SCHEMBL71800

CNC(CCC(C)=O)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 5/20 0.43
▸ NAALAD2 Q9Y3Q0 2/20 0.43
▸ RIMKLA Q8IXN7 1/20 0.43
▸ GGH Q92820 1/20 0.41
▸ ALDH1A1 P00352 2/20 0.39
▸ KDM4E B2RXH2 1/20 0.39
▸ MAPT P10636 1/20 0.39
▸ THRB P10828 1/20 0.39
▸ ALOX15 P16050 1/20 0.39
▸ NFKB1 P19838 1/20 0.39
▸ PTGS2 P35354 1/20 0.39
▸ THPO P40225 1/20 0.39
▸ RECQL P46063 1/20 0.39
▸ BLM P54132 1/20 0.39
▸ SMN1; SMN2 Q16637 1/20 0.39
▸ LMNA P02545 1/20 0.39
▸ SLC15A2 Q16348 1/20 0.39
▸ FNTA P49354 2/20 0.37
▸ FNTB P49356 2/20 0.37
▸ NOD1 Q9Y239 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22111315 1.00 FOLH1 (0.43) FOLH1NAALAD2RIMKLAGGHALDH1A1
SCHEMBL12118214 1.00 FOLH1 (0.43) FOLH1NAALAD2RIMKLAGGHALDH1A1
SCHEMBL21440833 0.89 NOD1 (0.53) FOLH1NAALAD2RIMKLAFNTAFNTB
SCHEMBL21242989 0.89 NOD1 (0.53) FOLH1NAALAD2RIMKLAFNTAFNTB
SCHEMBL12118226 0.89 NOD1 (0.53) FOLH1NAALAD2RIMKLAFNTAFNTB
SCHEMBL13377667 0.89 NOD1 (0.53) FOLH1NAALAD2RIMKLAFNTAFNTB
SCHEMBL21242721 0.89 NOD1 (0.53) FOLH1NAALAD2RIMKLAFNTAFNTB
SCHEMBL21440846 0.89 NOD1 (0.53) FOLH1NAALAD2RIMKLAFNTAFNTB
SCHEMBL12734745 0.86 FOLH1 (0.34) FOLH1NAALAD2RIMKLAGGHALDH1A1
SCHEMBL13475050 0.84 ALDH1A1 (0.41) FOLH1NAALAD2RIMKLAGGHALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240209028-A1 CNP COMPOUNDS NOVO NORDISK A/S (DK) 2024-06-27 — — US disclosed
WO-2024133739-A1 AMYLIN RECEPTOR AGONISTS NOVO NORDISK A/S (DK) 2024-06-27 — — WO disclosed
US-20240209028-A1 CNP COMPOUNDS NOVO NORDISK A/S (DK) 2024-06-27 — — US disclosed
WO-2024094747-A1 CNP COMPOUNDS NOVO NORDISK A/S (DK) 2024-05-10 — — WO disclosed
EP-3250191-B1 TABLETS COMPRISING GLP-1 AGONIST AND ENTERIC COATING NOVO NORDISK AS (DK) 2024-01-17 — — EP disclosed
US-20230330189-A1 ACYLATED GLP-1 DERIVATIVE Sciwind Biosciences Co., Ltd. (CN) 2023-10-19 — — US disclosed
US-20230330189-A1 ACYLATED GLP-1 DERIVATIVE Sciwind Biosciences Co., Ltd. (CN) 2023-10-19 — — US disclosed
US-20230295260-A1 GLP RECEPTOR AGONISTS HEPTARES THERAPEUTICS LIMITED (GB) 2023-09-21 — — US disclosed
WO-2023139106-A2 LONG-ACTING GIPR ANTAGONISTS NOVO NORDISK A/S (DK) 2023-07-27 — — WO disclosed
US-20230203100-A1 COMPOSITIONS INCLUDING MULTI-AGONIST PEPTIDES AND METHODS OF MANUFACTURE AND USE PEP2TANGO THERAPEUTICS INC. 2023-06-29 — — US disclosed
US-20090156478-A1 Acylated GLP-1 Compounds NOVO NORDISK A/S (DK) 2009-06-18 — — US disclosed
US-20090105118-A1 Preparation and applications of novel complexes made by gamma-polyglutamic acid and cisplatin YE HAIFENG 2009-04-23 — — US disclosed
US-20090092664-A1 POLYMER-METAL CHELATOR CONJUGATES AND USES THEREOF UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION 2009-04-09 — — US disclosed
US-20080262412-A1 Internal medical devices for delivery of therapeutic agent in conjunction with a source of electrical power BOSTON SCIENTIFIC SCIMED, INC. (US) 2008-10-23 — — US disclosed
US-20080207507-A1 Extended Glp-1 Compounds NOVO NORDISK A/S (DK) 2008-08-28 — — US disclosed
WO-2008023050-A1 ACYLATED EXENDIN-4 COMPOUNDS NOVO NORDISK A/S (DK) 2008-02-28 — — WO disclosed
US-20070272119-A1 Coating Composition, Coating Film, and Method of Reducing Underwater Friction NIPPON PAINT CO., LTD. (JP) 2007-11-29 — — US disclosed
US-20070178136-A1 Medical devices for therapeutic agent delivery with polymeric regions that contain copolymers having both soft segments and uniform length hard segments BOSTON SCIENTIFIC SCIMED, INC. 2007-08-02 — — US disclosed
US-20070178136-A1 Medical devices for therapeutic agent delivery with polymeric regions that contain copolymers having both soft segments and uniform length hard segments BOSTON SCIENTIFIC SCIMED, INC. 2007-08-02 — — US disclosed
US-20070099827-A1 Sialogogue, oral composition and fool product containing the same MEIJI SEIKA KAISHA, LTD. (JP) 2007-05-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080207507-A1 Extended Glp-1 Compounds GLP1R, GIPR, IAPP FOLH1 274/4885NAALAD2 485/4885RIMKLA 1572/4885
US-20090156478-A1 Acylated GLP-1 Compounds GLP1R, GIPR, GCGR FOLH1 450/4885NAALAD2 112/4885RIMKLA 742/4885
US-20230203100-A1 COMPOSITIONS INCLUDING MULTI-AGONIST PEPTIDES AND METHODS OF MANUFACTURE AND USE IAPP, GPR119, GIPR FOLH1 1596/4885NAALAD2 1715/4885RIMKLA 851/4885
US-20240209028-A1 CNP COMPOUNDS NPPA, NPR1, NPR3 FOLH1 562/4885NAALAD2 356/4885RIMKLA 1848/4885
US-20070099827-A1 Sialogogue, oral composition and fool product containing the same FUCA1, PGA5, FUCA2 FOLH1 276/4885NAALAD2 696/4885RIMKLA 1554/4885
US-20090092664-A1 POLYMER-METAL CHELATOR CONJUGATES AND USES THEREOF FIBP, ENPEP, SLC30A6 FOLH1 26/4885NAALAD2 255/4885RIMKLA 505/4885
US-20230295260-A1 GLP RECEPTOR AGONISTS GLP1R, GIPR, NPY4R FOLH1 2988/4885NAALAD2 493/4885RIMKLA 2945/4885
US-20090105118-A1 Preparation and applications of novel complexes made by gamma-polyglutamic acid and cisplatin GGCT, POLG, FPGS FOLH1 20/4885NAALAD2 381/4885RIMKLA 51/4885
US-20230330189-A1 ACYLATED GLP-1 DERIVATIVE GLP1R, GIPR, IAPP FOLH1 648/4885NAALAD2 247/4885RIMKLA 1548/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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