SCHEMBL2144101

SCHEMBL2144101

COC(=O)C=CC(=O)O[Si](C)(C)C

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 4/20 0.65
HCAR2 Q8TDS4 2/20 0.65
KEAP1 Q14145 1/20 0.65
ALDH1A1 P00352 6/20 0.38
KDM4E B2RXH2 4/20 0.38
MAPT P10636 4/20 0.38
TDP1 Q9NUW8 1/20 0.38
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
TYR P14679 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
CA14 Q9ULX7 1/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
GFPT1 Q06210 1/20 0.36
LMNA P02545 2/20 0.36
HTT P42858 1/20 0.36
ALOX15 P16050 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2144386 1.00 NFE2L2 (0.65) NFE2L2HCAR2KEAP1ALDH1A1KDM4E
SCHEMBL2144096 1.00 NFE2L2 (0.65) NFE2L2HCAR2KEAP1ALDH1A1KDM4E
SCHEMBL15186306 0.90 NFE2L2 (0.65) NFE2L2HCAR2KEAP1ALDH1A1KDM4E
SCHEMBL16004844 0.89 HCAR2 (0.45) NFE2L2HCAR2KEAP1ALDH1A1ATM
SCHEMBL6049197 0.89 HCAR2 (0.45) NFE2L2HCAR2KEAP1ALDH1A1ATM
SCHEMBL9615496 0.89 HCAR2 (0.45) NFE2L2HCAR2KEAP1ALDH1A1ATM
SCHEMBL15186537 0.85 NFE2L2 (0.65) NFE2L2HCAR2KEAP1ALDH1A1KDM4E
SCHEMBL15198323 0.82 NFE2L2 (0.54) NFE2L2HCAR2KEAP1ALDH1A1KDM4E
Dimethyl Fumarate SCHEMBL11668350 0.81 NFE2L2 (1.00) NFE2L2HCAR2KEAP1ALDH1A1KDM4E
Dimethyl Maleate SCHEMBL75864 0.81 NFE2L2 (1.00) NFE2L2HCAR2KEAP1ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2348077-B1 Antifouling composition JOTUN AS (NO) 2013-04-03 EP disclosed
WO-2011092143-A1 ANTIFOULING COMPOSITION JOTUN A/S (NO) 2011-08-04 WO disclosed
EP-2348077-A1 Antifouling composition Jotun A/S (NO) 2011-07-27 EP disclosed
EP-0790289-B1 Polymeric material for liquid crystal/polymer composite film, record display medium, and use thereof DAINIPPON PRINTING CO LTD (JP) 2001-09-05 EP disclosed
EP-0802243-B1 Coating composition NOF CORP (JP) 2001-06-27 EP disclosed
US-5851422-A Polymeric material for liquid crystal/polymer composite film, record display medium, and use thereof DAI NIPPON PRINTING CO., LTD. (JP) 1998-12-22 US disclosed
US-5795374-A SILYL ACRYLATE POLYMERS NOF CORPORATION (JP) 1998-08-18 US disclosed
EP-0802243-A2 Coating composition NOF CORPORATION (JP) 1997-10-22 EP disclosed
EP-0790289-A1 Polymeric material for liquid crystal/polymer composite film, liquid crystal/polymer composite film, record display medium, and use thereof DAI NIPPON PRINTING CO., LTD. (JP) 1997-08-20 EP disclosed