Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 3/20 | 0.40 |
| ▸ | WNT3A | P56704 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
| ▸ | QPCT | Q16769 | 3/20 | 0.32 |
| ▸ | QPCTL | Q9NXS2 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21441134 | 0.86 | CTNNB1 (0.51) | CTNNB1WNT3AKDM4EALDH1A1HTT | |
| SCHEMBL21441296 | 0.85 | CTNNB1 (0.42) | CTNNB1WNT3AKDM4EALDH1A1HTT | |
| SCHEMBL21441154 | 0.84 | CTNNB1 (0.38) | CTNNB1WNT3AKDM4EALDH1A1HTT | |
| SCHEMBL21441284 | 0.83 | NAMPT (0.44) | CTNNB1WNT3AKDM4EALDH1A1HTT | |
| SCHEMBL21441397 | 0.82 | QPCT (0.40) | CTNNB1WNT3AKDM4EALDH1A1HTT | |
| SCHEMBL21441188 | 0.82 | HTT (0.44) | CTNNB1WNT3AKDM4EALDH1A1HTT | |
| SCHEMBL21441203 | 0.81 | CTNNB1 (0.41) | CTNNB1WNT3AKDM4EALDH1A1HTT | |
| SCHEMBL21441252 | 0.81 | ALPL (0.42) | CTNNB1WNT3AKDM4EALDH1A1HTT | |
| SCHEMBL21441240 | 0.81 | CTNNB1 (0.36) | CTNNB1WNT3AKDM4EALDH1A1HTT | |
| SCHEMBL21441405 | 0.81 | CTNNB1 (0.37) | CTNNB1WNT3AKDM4EALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3206686-B1 | GAMMA-DIKETONES FOR TREATMENT AND PREVENTION OF AGING SKIN AND WRINKLES | SAMUMED LLC (US) | 2019-10-09 | — | — | EP | disclosed |