Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.38 |
| ▸ | WNT3A | P56704 | 2/20 | 0.38 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 2/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21441252 | 0.88 | ALPL (0.42) | TDP1KMT2ARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL21441134 | 0.87 | CTNNB1 (0.51) | QPCTTDP1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL21441188 | 0.86 | HTT (0.44) | QPCTRAB9ASMN1; SMN2CTNNB1WNT3A | |
| SCHEMBL21441154 | 0.86 | CTNNB1 (0.38) | QPCTTDP1RAB9ASMN1; SMN2CTNNB1 | |
| SCHEMBL21441354 | 0.83 | CTNNB1 (0.40) | TDP1KMT2ARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL21441148 | 0.82 | MAPT (0.47) | QPCTRAB9ASMN1; SMN2NPC1CTNNB1 | |
| SCHEMBL21441405 | 0.82 | CTNNB1 (0.37) | QPCTTDP1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL21441236 | 0.82 | CTNNB1 (0.40) | QPCTTDP1RAB9ASMN1; SMN2CTNNB1 | |
| SCHEMBL15980124 | 0.80 | CTNNB1 (0.60) | TDP1KMT2ARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL21441240 | 0.80 | CTNNB1 (0.36) | QPCTTDP1RAB9ASMN1; SMN2CTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3206686-B1 | GAMMA-DIKETONES FOR TREATMENT AND PREVENTION OF AGING SKIN AND WRINKLES | SAMUMED LLC (US) | 2019-10-09 | — | — | EP | disclosed |