Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 7/20 | 0.69 |
| ▸ | WNT3A | P56704 | 7/20 | 0.69 |
| ▸ | TRPA1 | O75762 | 12/20 | 0.51 |
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21441429 | 0.83 | CTNNB1 (0.53) | CTNNB1WNT3ATRPA1TRPM8TRPV1 | |
| SCHEMBL21441278 | 0.82 | CTNNB1 (0.51) | CTNNB1WNT3ATRPA1 | |
| SCHEMBL21441419 | 0.82 | CTNNB1 (0.50) | CTNNB1WNT3ATRPA1TRPM8 | |
| SCHEMBL15969173 | 0.81 | CTNNB1 (1.00) | CTNNB1WNT3ATRPA1TRPM8 | |
| SCHEMBL21441262 | 0.81 | CTNNB1 (0.66) | CTNNB1WNT3A | |
| SCHEMBL21441201 | 0.81 | CTNNB1 (0.67) | CTNNB1WNT3A | |
| SCHEMBL21441283 | 0.81 | CTNNB1 (0.50) | CTNNB1WNT3ATRPA1TRPM8 | |
| SCHEMBL21441380 | 0.80 | CTNNB1 (0.52) | CTNNB1WNT3ATRPA1 | |
| SCHEMBL21441266 | 0.80 | CTNNB1 (0.48) | CTNNB1WNT3ATRPA1TRPM8 | |
| SCHEMBL21441367 | 0.77 | CTNNB1 (0.67) | CTNNB1WNT3ATRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3206686-B1 | GAMMA-DIKETONES FOR TREATMENT AND PREVENTION OF AGING SKIN AND WRINKLES | SAMUMED LLC (US) | 2019-10-09 | — | — | EP | disclosed |