Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 8/20 | 0.48 |
| ▸ | WNT3A | P56704 | 8/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | CLK2 | P49760 | 2/20 | 0.38 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21441262 | 0.81 | CTNNB1 (0.66) | CTNNB1WNT3ACLK2GSK3BCDK5 | |
| SCHEMBL21441341 | 0.80 | CLK1 (0.51) | CTNNB1WNT3ACLK2GSK3BCDK5 | |
| SCHEMBL15980153 | 0.80 | CTNNB1 (0.68) | CTNNB1WNT3AMEN1ALDH1A1HPGD | |
| SCHEMBL21441313 | 0.80 | CTNNB1 (0.69) | CTNNB1WNT3ATRPA1TRPM8 | |
| SCHEMBL21441398 | 0.80 | CTNNB1 (0.65) | CTNNB1WNT3AGAAMAPTRAB9A | |
| SCHEMBL21441365 | 0.78 | CTNNB1 (0.54) | CTNNB1WNT3ACLK2GSK3BCDK5 | |
| SCHEMBL21441263 | 0.78 | CTNNB1 (0.67) | CTNNB1WNT3ATRPA1ROCK1NOS1 | |
| SCHEMBL21441407 | 0.78 | CTNNB1 (0.50) | CTNNB1WNT3ACLK2GSK3BCDK5 | |
| SCHEMBL21441367 | 0.78 | CTNNB1 (0.67) | CTNNB1WNT3ATRPA1CLK2GSK3B | |
| SCHEMBL21441337 | 0.77 | ROCK2 (0.56) | CTNNB1WNT3ATRPA1CLK2GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3206686-B1 | GAMMA-DIKETONES FOR TREATMENT AND PREVENTION OF AGING SKIN AND WRINKLES | SAMUMED LLC (US) | 2019-10-09 | — | — | EP | disclosed |