Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 7/20 | 0.50 |
| ▸ | WNT3A | P56704 | 7/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | METAP2 | P50579 | 1/20 | 0.46 |
| ▸ | CDC7 | O00311 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | DDR2 | Q16832 | 3/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21441419 | 0.89 | CTNNB1 (0.50) | CTNNB1WNT3AMEN1POLBKMT2A | |
| SCHEMBL15980142 | 0.85 | CTNNB1 (0.70) | CTNNB1WNT3AMEN1POLBKMT2A | |
| SCHEMBL21441337 | 0.84 | ROCK2 (0.56) | CTNNB1WNT3ACDC7TRPA1ROCK2 | |
| SCHEMBL21441262 | 0.83 | CTNNB1 (0.66) | CTNNB1WNT3AROCK2 | |
| SCHEMBL21441417 | 0.81 | CTNNB1 (0.55) | CTNNB1WNT3ATRPA1ROCK2 | |
| SCHEMBL21441313 | 0.81 | CTNNB1 (0.69) | CTNNB1WNT3ATRPA1TRPM8 | |
| SCHEMBL21441225 | 0.80 | CTNNB1 (0.48) | CTNNB1WNT3AS1PR1 | |
| SCHEMBL21441367 | 0.79 | CTNNB1 (0.67) | CTNNB1WNT3AMEN1KMT2AMETAP2 | |
| SCHEMBL21441401 | 0.79 | CTNNB1 (0.53) | CTNNB1WNT3AMEN1KMT2AMETAP2 | |
| SCHEMBL21441365 | 0.77 | CTNNB1 (0.54) | CTNNB1WNT3AMEN1KMT2AMETAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3206686-B1 | GAMMA-DIKETONES FOR TREATMENT AND PREVENTION OF AGING SKIN AND WRINKLES | SAMUMED LLC (US) | 2019-10-09 | — | — | EP | disclosed |