Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 7/20 | 0.48 |
| ▸ | WNT3A | P56704 | 7/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 6/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.37 |
| ▸ | CLK2 | P49760 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21441408 | 0.86 | CTNNB1 (0.51) | CTNNB1WNT3ATRPA1ESR1NPC1 | |
| SCHEMBL21441429 | 0.83 | CTNNB1 (0.53) | CTNNB1WNT3ATRPA1TRPV1 | |
| SCHEMBL21441365 | 0.83 | CTNNB1 (0.54) | CTNNB1WNT3AESR1NPC1CLK1 | |
| SCHEMBL21441304 | 0.82 | CTNNB1 (0.48) | CTNNB1WNT3ARAB9A | |
| SCHEMBL21441278 | 0.82 | CTNNB1 (0.51) | CTNNB1WNT3ATRPA1ESR1NPC1 | |
| SCHEMBL15988714 | 0.81 | CTNNB1 (0.66) | CTNNB1WNT3ATRPA1ESR1NPC1 | |
| SCHEMBL21441263 | 0.80 | CTNNB1 (0.67) | CTNNB1WNT3ATRPA1MEN1RAB9A | |
| SCHEMBL21441274 | 0.80 | CTNNB1 (0.67) | CTNNB1WNT3AESR1NPC1CLK1 | |
| SCHEMBL21441417 | 0.79 | CTNNB1 (0.55) | CTNNB1WNT3ATRPA1ESR1NPC1 | |
| SCHEMBL21441401 | 0.79 | CTNNB1 (0.53) | CTNNB1WNT3AESR1NPC1CLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3206686-B1 | GAMMA-DIKETONES FOR TREATMENT AND PREVENTION OF AGING SKIN AND WRINKLES | SAMUMED LLC (US) | 2019-10-09 | — | — | EP | disclosed |