Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GALR3 | O60755 | 1/20 | 0.35 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.35 |
| ▸ | GPR183 | P32249 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21511091 | 0.69 | MEN1 (0.73) | HPGDNPC1RAB9AMEN1KMT2A | |
| SCHEMBL21442503 | 0.67 | SMN1; SMN2 (0.41) | HPGDNPC1RAB9AMEN1KMT2A | |
| SCHEMBL20159034 | 0.67 | SMN1; SMN2 (0.46) | HPGDNPC1RAB9AMEN1KMT2A | |
| SCHEMBL16901934 | 0.67 | SMN1; SMN2 (0.57) | HPGDNPC1RAB9AMEN1KMT2A | |
| SCHEMBL12722375 | 0.66 | MEN1 (0.71) | HPGDNPC1RAB9AMEN1KMT2A | |
| SCHEMBL9096210 | 0.65 | MEN1 (0.70) | HPGDNPC1RAB9AMEN1KMT2A | |
| SCHEMBL4454097 | 0.65 | ALDH1A1 (0.47) | HPGDNPC1RAB9ACYP3A4CYP2D6 | |
| SCHEMBL3477950 | 0.65 | RARB (0.55) | HPGDNPC1RAB9AMEN1KMT2A | |
| SCHEMBL3477945 | 0.65 | RARB (0.55) | HPGDNPC1RAB9AMEN1KMT2A | |
| SCHEMBL7538660 | 0.63 | HSD11B1 (0.49) | HPGDCYP3A4CYP2D6CYP2C9SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2882719-B1 | PYRIDAZIN-3(2H)-ONE DERIVATIVES AS IMAGING AGENTS FOR DETECTING MYOCARDIAL PERFUSION | LANTHEUS MEDICAL IMAGING INC (US) | 2019-10-09 | — | — | EP | disclosed |