Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5211841 | 0.83 | MEN1 (0.47) | MEN1KMT2AAHRMAPTHPGD | |
| SCHEMBL3865834 | 0.81 | NFKB1 (0.43) | MEN1KMT2AMAPTALDH1A1POLB | |
| SCHEMBL29827391 | 0.81 | NFKB1 (0.43) | MEN1KMT2AMAPTALDH1A1POLB | |
| SCHEMBL17773665 | 0.81 | MEN1 (0.51) | MEN1KMT2AAHRMAPTHPGD | |
| SCHEMBL29506595 | 0.79 | MAPT (0.61) | MEN1KMT2AMAPTHPGDALDH1A1 | |
| SCHEMBL188686 | 0.79 | MAPT (0.61) | MEN1KMT2AMAPTHPGDALDH1A1 | |
| SCHEMBL25014139 | 0.79 | ALDH1A1 (0.40) | KMT2AMAPTALDH1A1POLBNPC1 | |
| SCHEMBL2012010 | 0.78 | MAPT (0.46) | MEN1KMT2AAHRMAPTHPGD | |
| SCHEMBL2226205 | 0.78 | MEN1 (0.60) | MEN1KMT2AAHRMAPTHPGD | |
| SCHEMBL5656811 | 0.78 | MEN1 (0.51) | MEN1KMT2AAHRMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3549934-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | Celgene CAR LLC (BM) | 2019-10-09 | — | — | EP | disclosed |