Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PHGDH | O43175 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10660097 | 0.91 | ALDH1A1 (0.50) | POLBALDH1A1MEN1KMT2APHGDH | |
| SCHEMBL15589116 | 0.81 | POLB (0.44) | POLBALDH1A1MEN1KMT2APHGDH | |
| SCHEMBL10662365 | 0.80 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2APHGDHMGLL | |
| SCHEMBL10664302 | 0.80 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2APHGDHMGLL | |
| SCHEMBL24242893 | 0.77 | ALDH1A1 (0.61) | POLBALDH1A1MEN1KMT2APHGDH | |
| SCHEMBL12243151 | 0.77 | ALDH1A1 (0.61) | POLBALDH1A1MEN1KMT2APHGDH | |
| SCHEMBL11225337 | 0.77 | ALDH1A1 (0.42) | ALDH1A1PHGDHMGLLHPGDCYP1A2 | |
| SCHEMBL22142664 | 0.76 | PHGDH (0.42) | POLBALDH1A1MEN1KMT2APHGDH | |
| SCHEMBL18457377 | 0.75 | ALDH1A1 (0.43) | POLBALDH1A1MEN1KMT2APHGDH | |
| SCHEMBL2606069 | 0.74 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2APHGDHMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3549934-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | Celgene CAR LLC (BM) | 2019-10-09 | — | — | EP | disclosed |