Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10662365 | 0.96 | ALDH1A1 (0.45) | ALDH1A1HPGDMAPTKDM4ETP53 | |
| SCHEMBL10664302 | 0.96 | ALDH1A1 (0.45) | ALDH1A1HPGDMAPTKDM4ETP53 | |
| SCHEMBL17122535 | 0.81 | CA2 (0.60) | ALDH1A1KDM4ECA2CA1CA12 | |
| SCHEMBL21443542 | 0.77 | POLB (0.44) | ALDH1A1HPGDMAPTCYP1A2CYP2C9 | |
| SCHEMBL28865874 | 0.73 | ALDH1A1 (0.35) | ALDH1A1HPGDMAPTALOX15HSD17B10 | |
| SCHEMBL8275093 | 0.72 | ALDH1A1 (0.33) | ALDH1A1HPGDMAPTKDM4ETP53 | |
| SCHEMBL607804 | 0.72 | — | — | |
| SCHEMBL18288194 | 0.72 | — | — | |
| SCHEMBL14223425 | 0.72 | — | — | |
| SCHEMBL12162909 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4338428-A | Novel polyamides from ketene-aminals | THE UPJOHN COMPANY (US) | 1982-07-06 | — | — | US | claimed |
| US-11572355-B2 | Methods for synthesizing vinylidenes and alkenes | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) | 2023-02-07 | — | — | US | disclosed |
| US-20220017494-A1 | METHODS FOR SYNTHESIZING VINYLIDENES AND ALKENES | UNITED STATES DEPARTMENT OF ENERGY | 2022-01-20 | — | — | US | disclosed |
| EP-2026754-B1 | LIGHTENING AND/OR COLOURING AGENT COMPRISING CYCLIC UREA DERIVATIVES | HENKEL AG & CO KGAA (DE) | 2015-09-30 | — | — | EP | disclosed |
| US-4342841-A | Polyamide polyurethane prepared by reaction of polyisocyanate with a 1,1-diamino ethylene | THE UPJOHN COMPANY (US) | 1982-08-03 | — | — | US | disclosed |
| US-4338428-A | Novel polyamides from ketene-aminals | THE UPJOHN COMPANY (US) | 1982-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11572355-B2 | Methods for synthesizing vinylidenes and alkenes | ALKBH2, VAV1, ALKBH3 | ALDH1A1 474/4885HPGD 985/4885MAPT 4200/4885 |
| US-20220017494-A1 | METHODS FOR SYNTHESIZING VINYLIDENES AND ALKENES | ALKBH2, VAV1, ALKBH3 | ALDH1A1 474/4885HPGD 985/4885MAPT 4200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.