Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL27497036 | 1.00 | — | — | |
| Bromide SCHEMBL29077788 | 1.00 | — | — | |
| Bromide SCHEMBL23326424 | 1.00 | — | — | |
| Bromide SCHEMBL6946786 | 0.82 | — | — | |
| Bromide SCHEMBL7934370 | 0.82 | — | — | |
| Bromide SCHEMBL28849160 | 0.82 | — | — | |
| Bromide SCHEMBL3456702 | 0.82 | — | — | |
| Bromide SCHEMBL3592835 | 0.82 | — | — | |
| Bromide SCHEMBL21618410 | 0.82 | — | — | |
| Bromide SCHEMBL433673 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021043227-A1 | COATED GRANULE, SOLID DISPERSION, AND PREPARATION CONTAINING VORTIOXETINE HYDROBROMIDE FOR ORAL TASTE MASKING | 普济生物科技（台州）有限公司 | 2021-03-11 | — | — | WO | disclosed |
| CN-106860465-B | A kind of Gastrodin compound and its preparation | 昆药集团股份有限公司 | 2018-11-02 | — | — | CN | disclosed |
| CN-108558982-A | A kind of Novel acetate Ulipristal and its method for manufacturing | 郑州泰丰制药有限公司 | 2018-09-21 | — | — | CN | disclosed |
| CN-106083660-B | A kind of preparation process of 1- amino -4- bromo anthraquinone -2- sodium sulfonates | 南通市争妍新材料科技有限公司 | 2018-06-26 | — | — | CN | disclosed |
| CN-207537399-U | C5 of the cracking of ethylene rich in alkene raffinates oil hydrogenation plant | 新疆寰球工程公司 | 2018-06-26 | — | — | CN | disclosed |
| CN-106860465-A | A kind of Gastrodin compound and its preparation | 昆药集团股份有限公司 | 2017-06-20 | — | — | CN | disclosed |
| CN-105524127-B | Gastrodin compound and preparation thereof | 昆药集团股份有限公司 | 2017-03-01 | — | — | CN | disclosed |
| CN-105524127-A | Gastrodin compound and preparation thereof | KPC PHARMACEUTICALS INC | 2016-04-27 | — | — | CN | disclosed |
| EP-2344494-B1 | AMINOTRIAZOLOPYRIDINES AND THEIR USE AS KINASE INHIBITORS | SIGNAL PHARM LLC (US) | 2016-04-20 | — | — | EP | disclosed |
| CN-102827041-B | Preparation method of p-methylsulfurylbenzaldehyde | ZHANGJIAGANG XINYI CHEMICAL CO LTD | 2014-04-16 | — | — | CN | disclosed |
| CN-102918018-A | Process for producing terephthalic acid | UOP LLC | 2013-02-06 | — | — | CN | disclosed |
| US-20130005707-A1 | AMINOTRIAZOLOPYRIDINES, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | BAHMANYAR SOGOLE (US) | 2013-01-03 | — | — | US | disclosed |
| US-8299056-B2 | Aminotriazolopyridines, compositions thereof, and methods of treatment therewith | SIGNAL PHARMACEUTICALS, LLC (US) | 2012-10-30 | — | — | US | disclosed |
| EP-2344494-A1 | AMINOTRIAZOLOPYRIDINES AND THEIR USE AS KINASE INHIBITORS | Signal Pharmaceuticals, LLC (US) | 2011-07-20 | — | — | EP | disclosed |
| CN-101219935-B | Bromol production method | SICHUAN DONGCAI TECHNOLOGY GROUP CO LTD | 2010-11-17 | — | — | CN | disclosed |
| US-20100093698-A1 | AMINOTRIAZOLOPYRIDINES, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | SIGNAL PHARMACEUTICALS, LLC | 2010-04-15 | — | — | US | disclosed |
| WO-2010027500-A1 | AMINOTRIAZOLOPYRIDINES AND THEIR USE AS KINASE INHIBITORS | SIGNAL PHARMACEUTICALS, LLC (US) | 2010-03-11 | — | — | WO | disclosed |
| CN-100462362-C | Preparing process of 2-(10-oxy-10,11-dihydrodibenz [b,f]-thiotropilium-2-yl) propionic acid | CHANGZHOU KANGRUI CHEMICAL CO (CN) | 2009-02-18 | — | — | CN | disclosed |
| CN-1986542-A | Preparing process of 2-(10-oxy-10,11-dihydrodibenz [b,f]-thiotropilium-2-yl) propionic acid | KANGRUI CHEMICAL CO LTD CHANGZ (CN) | 2007-06-27 | — | — | CN | disclosed |
| CN-1964946-A | 2-propen-1-ones as HSP 70 inducers | TORRENT PHARMACEUTICALS LTD (IN) | 2007-05-16 | — | — | CN | disclosed |