Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL6946786 | 1.00 | — | — | |
| Bromide SCHEMBL3456703 | 0.87 | — | — | |
| Bromide SCHEMBL8904552 | 0.87 | — | — | |
| Bromide SCHEMBL7937591 | 0.87 | — | — | |
| Bromide SCHEMBL23326424 | 0.82 | — | — | |
| Bromide SCHEMBL29077788 | 0.82 | — | — | |
| Bromide SCHEMBL401797 | 0.82 | — | — | |
| Bromide SCHEMBL1524665 | 0.82 | — | — | |
| Bromide SCHEMBL2144385 | 0.82 | — | — | |
| Bromide SCHEMBL27497036 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4267591-A2 | ORGANOMETALLIC COMPOUNDS | Umicore AG & Co. KG (DE) | 2023-11-01 | — | — | EP | claimed |
| US-9452229-B2 | Highly concentrated, biocidally active compositions and aqueous mixtures and methods of making the same | ALBEMARLE CORPORATION (US) | 2016-09-27 | — | — | US | claimed |
| WO-2007142618-A2 | HIGH CONCENTRATED, BIOCIDALLY ACTIVE COMPOSITIONS AND AQUEOUS MIXTURES AND METHODS OF MAKING THE SAME | ALBEMARLE CORPORATION (US) | 2007-12-13 | — | — | WO | claimed |
| US-20060278586-A1 | Highly concentrated, biocidally active compositions and aqueous mixtures and methods of making the same | ALBEMARLE CORPORATION | 2006-12-14 | — | — | US | claimed |
| CN-1189448-A | Method of preparing hydrobromic acid by utilizing tail gas containng bromine | YE XILAI (CN) | 1998-08-05 | — | — | CN | claimed |
| EP-4365174-A1 | METHOD FOR PRODUCING BENZOXAZOLE DERIVATIVE HAVING BICYCLIC PIPERAZINE RING OR SALT THEREOF, AND METHOD FOR PRODUCING MATERIAL THEREOF | Meiji Seika Pharma Co., Ltd. (JP) | 2024-05-08 | — | — | EP | disclosed |
| EP-4330228-A1 | G-ALPHA-S INHIBITORS AND USES THEREOF | The Regents of the University of California (US) | 2024-03-06 | — | — | EP | disclosed |
| CN-117295744-A | Method for producing benzoxazole derivative having bicyclic piperazine ring or salt thereof, and method for producing raw material therefor | 明治制果药业株式会社 | 2023-12-26 | — | — | CN | disclosed |
| CN-116847837-A | Improved synthesis of CRAC channel inhibitors | 钙医学公司 | 2023-10-03 | — | — | CN | disclosed |
| EP-4243813-A1 | IMPROVED SYNTHESIS OF CRAC CHANNEL INHIBITORS | Calcimedica, Inc. (US) | 2023-09-20 | — | — | EP | disclosed |
| US-20230029301-A1 | SCALEABLE PREPARATION OF POLYKETIDES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-01-26 | — | — | US | disclosed |
| EP-4009966-A1 | SCALEABLE PREPARATION OF POLYKETIDES | The Regents of the University of California (US) | 2022-06-15 | — | — | EP | disclosed |
| WO-2001035745-A1 | CONCENTRATED AQUEOUS BROMINE SOLUTIONS AND THEIR PREPARATION | ALBEMARLE CORPORATION (US) | 2001-05-25 | — | — | WO | disclosed |
| US-6204294-B1 | GUANIDINE CONTAINING COMPOUNDS | SMITHKLINE BEECHAM CORPORATION | 2001-03-20 | — | — | US | disclosed |
| WO-2000076516-A1 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-12-21 | — | — | WO | disclosed |
| US-6156229-A | Stable oxidizing bromine formulations, method of manufacture and uses thereof for biofouling control | NALCO CHEMICAL COMPANY (US) | 2000-12-05 | — | — | US | disclosed |
| WO-2000064806-A1 | STABLE OXIDIZING BROMINE FORMULATIONS, METHOD OF MANUFACTURE AND USES THEREOF FOR BIOFOULING CONTROL | NALCO CHEMICAL COMPANY (US) | 2000-11-02 | — | — | WO | disclosed |
| US-6123870-A | Stable oxidizing bromine formulations, method of manufacture and uses thereof for biofouling control | NALCO CHEMICAL COMPANY (US) | 2000-09-26 | — | — | US | disclosed |
| CN-1232398-A | IL-8 receptor antagonists | SMITHKLINE BEECHAM CORP (US) | 1999-10-20 | — | — | CN | disclosed |
| CN-1189448-A | Method of preparing hydrobromic acid by utilizing tail gas containng bromine | YE XILAI (CN) | 1998-08-05 | — | — | CN | disclosed |