Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23869542 | 0.72 | — | — | |
| SCHEMBL11695825 | 0.70 | POLB (0.41) | POLB | |
| SCHEMBL3499885 | 0.69 | ATM (0.58) | TSHRCYP2C9CYP2C19POLBALDH1A1 | |
| SCHEMBL1274700 | 0.69 | ATM (0.58) | TSHRCYP2C9CYP2C19POLBALDH1A1 | |
| SCHEMBL27925079 | 0.69 | ATM (0.58) | TSHRCYP2C9CYP2C19POLBALDH1A1 | |
| SCHEMBL765300 | 0.68 | ATM (0.54) | TSHRCYP2C9CYP2C19POLBALDH1A1 | |
| SCHEMBL22804064 | 0.68 | ESR1 (0.56) | TSHRALDH1A1 | |
| SCHEMBL10587222 | 0.68 | ESR1 (0.56) | TSHRALDH1A1 | |
| SCHEMBL29057553 | 0.68 | ESR1 (0.56) | TSHRALDH1A1 | |
| SCHEMBL10793379 | 0.68 | FOLH1 (0.43) | TSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3134125-B1 | ANTIBODY-DRUG-CONJUGATE AND ITS USE FOR THE TREATMENT OF CANCER | PF MEDICAMENT (FR) | 2019-10-09 | — | — | EP | disclosed |