Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | MIF | P14174 | 2/20 | 0.52 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MDM4 | O15151 | 1/20 | 0.52 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.52 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | NOS3 | P29474 | 1/20 | 0.45 |
| ▸ | NOS1 | P29475 | 1/20 | 0.45 |
| ▸ | NOS2 | P35228 | 1/20 | 0.45 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.44 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10587222 | 1.00 | ESR1 (0.56) | ESR1ESR2NPSR1KMT2AMIF | |
| SCHEMBL22804064 | 1.00 | ESR1 (0.56) | ESR1ESR2NPSR1KMT2AMIF | |
| SCHEMBL765300 | 0.88 | ATM (0.54) | ESR1ESR2NPSR1KMT2ALNPEP | |
| SCHEMBL1503825 | 0.86 | NOS2 (0.54) | NPSR1ALDH1A1NOS3NOS1NOS2 | |
| SCHEMBL11549702 | 0.86 | LNPEP (0.45) | ESR1ESR2NPSR1KMT2ALNPEP | |
| SCHEMBL6658615 | 0.86 | NOS2 (0.44) | ESR1ESR2NPSR1KMT2ALNPEP | |
| SCHEMBL6572040 | 0.86 | LNPEP (0.45) | ESR1ESR2NPSR1KMT2ALNPEP | |
| SCHEMBL3499885 | 0.86 | ATM (0.58) | KMT2ATSHRALDH1A1NOS3NOS1 | |
| SCHEMBL27925079 | 0.86 | ATM (0.58) | KMT2ATSHRALDH1A1NOS3NOS1 | |
| SCHEMBL1274700 | 0.86 | ATM (0.58) | KMT2ATSHRALDH1A1NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116617204-B | Application of phenol alkaloid in preparation of angiogenesis promoting medicine | 山东省科学院生物研究所 | 2024-03-12 | — | — | CN | claimed |
| CN-116617204-A | Application of phenol alkaloid in preparation of angiogenesis promoting medicine | 山东省科学院生物研究所 | 2023-08-22 | — | — | CN | claimed |
| CN-116617204-B | Application of phenol alkaloid in preparation of angiogenesis promoting medicine | 山东省科学院生物研究所 | 2024-03-12 | — | — | CN | disclosed |
| CN-116617204-B | Application of phenol alkaloid in preparation of angiogenesis promoting medicine | 山东省科学院生物研究所 | 2024-03-12 | — | — | CN | disclosed |
| CN-116617204-A | Application of phenol alkaloid in preparation of angiogenesis promoting medicine | 山东省科学院生物研究所 | 2023-08-22 | — | — | CN | disclosed |
| CN-116617204-A | Application of phenol alkaloid in preparation of angiogenesis promoting medicine | 山东省科学院生物研究所 | 2023-08-22 | — | — | CN | disclosed |