SCHEMBL21445264

SCHEMBL21445264

OCCN(CCO)CC(O)CN1c2ccccc2Sc2ccc(C(F)(F)F)cc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 13/20 1.00
MEN1 O00255 3/20 0.73
KMT2A Q03164 3/20 0.73
TP53 P04637 3/20 0.54
ABCB11 O95342 3/20 0.54
MAPK1 P28482 3/20 0.54
CYP1A2 P05177 2/20 0.54
CHRM2 P08172 2/20 0.54
ABCB1 P08183 2/20 0.54
HTR1A P08908 2/20 0.54
ADRA2A P08913 2/20 0.54
ADORA3 P0DMS8 2/20 0.54
CYP2D6 P10635 2/20 0.54
CHRM1 P11229 2/20 0.54
DRD1 P21728 2/20 0.54
SLC6A2 P23975 2/20 0.54
SLC6A4 P31645 2/20 0.54
ADRA1A P35348 2/20 0.54
OPRM1 P35372 2/20 0.54
DRD3 P35462 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30056638 1.00 FPR2 (1.00) FPR2MEN1KMT2ATP53ABCB11
SCHEMBL26001899 0.92 FPR2 (0.85) FPR2MEN1KMT2ATP53ABCB11
SCHEMBL26001911 0.92 FPR2 (0.85) FPR2MEN1KMT2ATP53ABCB11
SCHEMBL13167012 0.86 KMT2A (0.97) FPR2MEN1KMT2ATP53ABCB11
SCHEMBL26000537 0.86 FPR2 (0.75) FPR2MEN1KMT2ATP53ABCB11
SCHEMBL26000799 0.85 FPR2 (0.73) FPR2MEN1KMT2ATP53ABCB11
SCHEMBL1809214 0.85 FPR2 (0.73) FPR2MEN1KMT2ATP53ABCB11
SCHEMBL1809212 0.84 FPR2 (0.72) FPR2MEN1KMT2ATP53ABCB11
SCHEMBL21445254 0.83 FPR2 (0.72) FPR2MEN1KMT2ATP53ABCB11
SCHEMBL26002013 0.83 FPR2 (0.71) FPR2MEN1KMT2ATP53ABCB11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230257410-A1 PHENOTHIAZINE DERIVATIVES AND USES THEREOF CAMP4 THERAPEUTICS CORPORATION 2023-08-17 US disclosed
US-11542290-B2 Phenothiazine derivatives and uses thereof CAMP4 THERAPEUTICS CORPORATION (US) 2023-01-03 US disclosed
US-20210061837-A1 PHENOTHIAZINE DERIVATIVES AND USES THEREOF CAMP4 THERAPEUTICS CORPORATION 2021-03-04 US disclosed
WO-2019195789-A1 PHENOTHIAZINE DERIVATIVES AND USES THEREOF CAMP4 THERAPEUTICS CORPORATION (US) 2019-10-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210061837-A1 PHENOTHIAZINE DERIVATIVES AND USES THEREOF RPLP2, RPS2, RPLP1 FPR2 2716/4885MEN1 1826/4885KMT2A 1086/4885
US-20230257410-A1 PHENOTHIAZINE DERIVATIVES AND USES THEREOF RPLP2, RPS2, RPLP1 FPR2 2716/4885MEN1 1826/4885KMT2A 1086/4885
US-11542290-B2 Phenothiazine derivatives and uses thereof RPLP2, RPS2, RPLP1 FPR2 2716/4885MEN1 1826/4885KMT2A 1086/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.