Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 2/20 | 0.40 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23138592 | 0.80 | CES1 (0.39) | MAOA | |
| SCHEMBL19147026 | 0.79 | KMO (0.59) | KMO | |
| SCHEMBL13442275 | 0.79 | KMO (0.59) | KMOPRSS1PRSS2PRSS3HDAC8 | |
| SCHEMBL2135450 | 0.75 | KMO (0.55) | KMOPRSS1PRSS2PRSS3HDAC8 | |
| SCHEMBL20243662 | 0.75 | PRSS1 (0.64) | KMOPRSS1PRSS2PRSS3HDAC8 | |
| SCHEMBL14471520 | 0.73 | KMO (0.64) | KMOPRSS1PRSS2PRSS3HDAC8 | |
| SCHEMBL2845394 | 0.73 | KMO (0.64) | KMOPRSS1PRSS2PRSS3HDAC8 | |
| SCHEMBL24285452 | 0.72 | KMO (0.40) | KMOPRSS1PRSS2PRSS3HDAC8 | |
| SCHEMBL4804883 | 0.72 | KMO (0.62) | KMOPRSS1PRSS2PRSS3HDAC8 | |
| SCHEMBL16795802 | 0.72 | KMO (0.52) | KMOPRSS1PRSS2PRSS3HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019192954-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2019-10-10 | — | — | WO | disclosed |