Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CDC25B | P30305 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21446188 | 0.88 | KDM4E (0.37) | KDM4EATML3MBTL1MEN1MAPT | |
| SCHEMBL21446776 | 0.86 | KDM4E (0.37) | KDM4EATML3MBTL1MEN1MAPT | |
| SCHEMBL14681303 | 0.84 | KDM4E (0.37) | KDM4EATML3MBTL1MEN1MAPT | |
| SCHEMBL21446202 | 0.83 | HDAC4 (0.38) | KDM4EATML3MBTL1MEN1MAPT | |
| SCHEMBL23423888 | 0.83 | HDAC4 (0.38) | KDM4EATML3MBTL1MEN1MAPT | |
| SCHEMBL2859104 | 0.83 | ATM (0.35) | KDM4EATML3MBTL1MEN1MAPT | |
| SCHEMBL21446736 | 0.83 | RAB9A (0.32) | ATMALDH1A1RAB9ATP53CYP3A4 | |
| SCHEMBL21446426 | 0.83 | KDM4E (0.36) | KDM4EATML3MBTL1MEN1MAPT | |
| SCHEMBL25125395 | 0.82 | ALDH1A1 (0.33) | KDM4EATML3MBTL1MEN1MAPT | |
| SCHEMBL21446732 | 0.82 | KDM4E (0.39) | KDM4EATML3MBTL1GLAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019192954-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2019-10-10 | — | — | WO | disclosed |