Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | PI4KA | P42356 | 1/20 | 0.35 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.34 |
| ▸ | WNT3A | P56704 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2143719 | 0.94 | MAPT (0.36) | ALDH1A1MAPTMEN1KMT2AADORA1 | |
| SCHEMBL5036594 | 0.88 | PIK3CG (0.41) | ALDH1A1MAPTMEN1KMT2AADORA1 | |
| SCHEMBL2145077 | 0.88 | POLB (0.38) | ALDH1A1MAPTMEN1KMT2AADORA1 | |
| SCHEMBL2143767 | 0.87 | ALDH1A1 (0.43) | ALDH1A1MAPTMEN1KMT2AADORA1 | |
| SCHEMBL4514385 | 0.86 | ALDH1A1 (0.37) | ALDH1A1MAPTMEN1KMT2AADORA1 | |
| SCHEMBL2143898 | 0.86 | WNT3A (0.43) | ALDH1A1MAPTADORA1DYRK1AHPGD | |
| SCHEMBL11942161 | 0.85 | ADORA1 (0.37) | ALDH1A1MAPTMEN1KMT2AADORA1 | |
| SCHEMBL2143808 | 0.84 | NR1I2 (0.38) | ALDH1A1MAPTADORA1DYRK1API4KA | |
| SCHEMBL11942160 | 0.83 | PI4KA (0.36) | ALDH1A1MAPTMEN1KMT2AADORA1 | |
| SCHEMBL3947866 | 0.83 | CNR1 (0.42) | ALDH1A1MAPTADORA1DYRK1AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1802636-B1 | PI3 KINASES INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2013-03-27 | — | — | EP | disclosed |
| EP-2343303-A1 | PI3-kinase inhibitors | Boehringer Ingelheim International GmbH (DE) | 2011-07-13 | — | — | EP | disclosed |