Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 5/20 | 0.46 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.45 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.45 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22919755 | 0.89 | EHMT2 (0.54) | BACE1EHMT2EHMT1KMT2AIRAK4 | |
| Hydrochloric Acid SCHEMBL21437364 | 0.88 | EHMT2 (0.53) | BACE1EHMT2EHMT1KMT2AIRAK4 | |
| SCHEMBL22919765 | 0.85 | EHMT2 (0.56) | BACE1EHMT2EHMT1KMT2AIRAK4 | |
| Hydrochloric Acid SCHEMBL21437392 | 0.85 | BACE1 (0.52) | BACE1EHMT2EHMT1NUDT1KMT2A | |
| Hydrochloric Acid SCHEMBL21437347 | 0.84 | EHMT2 (0.55) | BACE1EHMT2EHMT1KMT2AIRAK4 | |
| SCHEMBL21437408 | 0.80 | BACE1 (0.53) | BACE1EHMT2EHMT1NUDT1KMT2A | |
| SCHEMBL21450755 | 0.79 | BACE1 (0.54) | BACE1EHMT2EHMT1NUDT1HDAC1 | |
| Hydrochloric Acid SCHEMBL21437366 | 0.79 | BACE1 (0.53) | BACE1EHMT2EHMT1NUDT1HDAC1 | |
| Hydrochloric Acid SCHEMBL21437074 | 0.76 | EHMT2 (0.56) | BACE1EHMT2EHMT1KMT2AADORA2A | |
| Hydrochloric Acid SCHEMBL28512158 | 0.76 | EHMT2 (0.56) | EHMT2EHMT1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019195493-A2 | SUBSTITUTED 2-AMINOBENZIMIDAZOLES ANALOGS AS ANTIBIOFILM AGENTS | OHIO STATE INNOVATION FOUNDATION (US) | 2019-10-10 | — | — | WO | disclosed |