Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 3/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30360729 | 0.87 | TAAR1 (0.51) | HTR2CDRD1TAAR1SLC6A2SLC6A4 | |
| SCHEMBL19813015 | 0.87 | TAAR1 (0.51) | HTR2CDRD1TAAR1SLC6A2SLC6A4 | |
| SCHEMBL30360691 | 0.87 | TAAR1 (0.51) | HTR2CDRD1TAAR1SLC6A2SLC6A4 | |
| SCHEMBL19812923 | 0.87 | TAAR1 (0.51) | HTR2CDRD1TAAR1SLC6A2SLC6A4 | |
| SCHEMBL30360721 | 0.87 | TAAR1 (0.51) | HTR2CDRD1TAAR1SLC6A2SLC6A4 | |
| SCHEMBL19812921 | 0.87 | TAAR1 (0.51) | HTR2CDRD1TAAR1SLC6A2SLC6A4 | |
| SCHEMBL21451736 | 0.84 | DRD1 (0.39) | L3MBTL4L3MBTL1DRD1HTR2AHRH1 | |
| SCHEMBL15319616 | 0.82 | DRD1 (0.42) | HTR2CDRD1HTR2ATAAR1ADRA2A | |
| SCHEMBL19824791 | 0.81 | OPRL1 (0.39) | L3MBTL4L3MBTL1DRD1HTR2AHRH1 | |
| SCHEMBL22446808 | 0.81 | HTR2A (0.39) | HTR2CL3MBTL4L3MBTL1DRD1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10927124-B2 | Compounds and compositions and uses thereof | SUNOVION PHARMACEUTICALS INC. (US) | 2021-02-23 | — | — | US | disclosed |
| US-20190308990-A1 | COMPOUNDS AND COMPOSITIONS AND USES THEREOF | SUNOVION PHARMACEUTICALS INC. | 2019-10-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10927124-B2 | Compounds and compositions and uses thereof | CHAT, ACHE, MAOB | HTR2C 190/4885L3MBTL4 4502/4885L3MBTL1 4456/4885 |
| US-20190308990-A1 | COMPOUNDS AND COMPOSITIONS AND USES THEREOF | CHAT, ACHE, MAOB | HTR2C 190/4885L3MBTL4 4502/4885L3MBTL1 4456/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.