Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 16/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 16/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22966846 | 0.94 | PDCD1 (0.43) | PDCD1CD274HDAC3HDAC1HDAC6 | |
| SCHEMBL22966696 | 0.81 | PDCD1 (0.42) | PDCD1CD274HDAC3HDAC1HDAC6 | |
| SCHEMBL22966498 | 0.80 | PDCD1 (0.41) | PDCD1CD274HDAC3HDAC1HDAC6 | |
| SCHEMBL22966709 | 0.79 | HDAC6 (0.42) | PDCD1CD274HDAC3HDAC1HDAC6 | |
| SCHEMBL21451792 | 0.78 | PDCD1 (0.45) | PDCD1CD274HDAC3HDAC1HDAC6 | |
| SCHEMBL21451984 | 0.78 | HDAC6 (0.44) | PDCD1CD274HDAC3HDAC1HDAC6 | |
| SCHEMBL22966641 | 0.77 | PDCD1 (0.44) | PDCD1CD274HDAC3HDAC1HDAC6 | |
| SCHEMBL21451803 | 0.77 | PDCD1 (0.42) | PDCD1CD274 | |
| SCHEMBL22966819 | 0.76 | PDCD1 (0.42) | PDCD1CD274 | |
| SCHEMBL21452331 | 0.76 | ROCK2 (0.46) | PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019192506-A1 | IMMUNOMODULATORS, COMPOSITIONS AND METHODS THEREOF | BETTA PHARMACEUTICALS CO., LTD (CN) | 2019-10-10 | — | — | WO | disclosed |