Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.42 |
| ▸ | PDCD1 | Q15116 | 13/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 13/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22966498 | 0.90 | PDCD1 (0.41) | HDAC6HDAC3HDAC1PDCD1CD274 | |
| SCHEMBL22966696 | 0.87 | PDCD1 (0.42) | HDAC6HDAC3HDAC1PDCD1CD274 | |
| SCHEMBL22966846 | 0.85 | PDCD1 (0.43) | HDAC6HDAC3HDAC1PDCD1CD274 | |
| SCHEMBL21451792 | 0.84 | PDCD1 (0.45) | HDAC6HDAC3HDAC1PDCD1CD274 | |
| SCHEMBL21451984 | 0.84 | HDAC6 (0.44) | HDAC6HDAC3HDAC1PDCD1CD274 | |
| SCHEMBL21451803 | 0.83 | PDCD1 (0.42) | PDCD1CD274 | |
| SCHEMBL22966819 | 0.82 | PDCD1 (0.42) | PDCD1CD274 | |
| SCHEMBL21452332 | 0.82 | PDCD1 (0.42) | PDCD1CD274 | |
| SCHEMBL22966502 | 0.82 | PDCD1 (0.53) | HDAC6HDAC3HDAC1PDCD1CD274 | |
| SCHEMBL21452331 | 0.81 | ROCK2 (0.46) | PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210040118-A1 | IMMUNOMODULATORS, COMPOSITIONS AND METHODS THEREOF | BETTA PHARMACEUTICALS CO., LTD (CN) | 2021-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210040118-A1 | IMMUNOMODULATORS, COMPOSITIONS AND METHODS THEREOF | IL2, IL5, TSLP | HDAC6 390/4885HDAC3 1424/4885HDAC1 875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.