Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 3/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RBP4 | P02753 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | IL6 | P05231 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16212148 | 0.88 | HTR2C (0.49) | GAATDP1HTR2CHCRTR1HCRTR2 | |
| SCHEMBL25378056 | 0.88 | HTR2C (0.49) | GAATDP1HTR2CHCRTR1HCRTR2 | |
| SCHEMBL31227327 | 0.88 | HTR2C (0.49) | GAATDP1HTR2CHCRTR1HCRTR2 | |
| SCHEMBL21452450 | 0.86 | TAS1R3 (0.42) | GAATDP1HTR2CHTR2B | |
| SCHEMBL21452532 | 0.81 | AR (0.39) | — | |
| SCHEMBL10356725 | 0.78 | KDM4E (0.45) | GAAMAPTMCL1 | |
| SCHEMBL28007099 | 0.78 | NPC1 (0.43) | MAPTMCL1 | |
| SCHEMBL21452480 | 0.77 | P2RX7 (0.36) | GAARBP4MCL1 | |
| SCHEMBL22731163 | 0.75 | GAA (0.47) | GAATDP1HTR2CHCRTR1HCRTR2 | |
| SCHEMBL22727368 | 0.75 | GAA (0.47) | GAATDP1HTR2CHCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210171487-A1 | AROMATIC COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | SHANGHAI JIANHE PHARMACEUTICAL & TECHNOLOGY CO. LTD. (CN) | 2021-06-10 | — | — | US | disclosed |
| EP-3778579-A1 | AROMATIC COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Jianhe Pharmaceutical & Technology Co. Ltd. (CN) | 2021-02-17 | — | — | EP | disclosed |
| WO-2020237748-A1 | METHOD FOR PREPARING LONG-ACTING COMPOUND | 北京大学深圳研究生院 | 2020-12-03 | — | — | WO | disclosed |
| WO-2020237747-A1 | APPLICATIONS OF LONG-ACTING COMPOUND IN PREPARING MEDICAMENT | 北京大学深圳研究生院 | 2020-12-03 | — | — | WO | disclosed |
| WO-2020237749-A1 | LONG-ACTING COMPOUND | 北京大学深圳研究生院 | 2020-12-03 | — | — | WO | disclosed |
| WO-2019192602-A1 | AROMATIC COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海键合医药科技有限公司 | 2019-10-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210171487-A1 | AROMATIC COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | CYP4F11, PAH, COMT | GAA 728/4885TDP1 814/4885HTR2C 1307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.