Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | CLPP | Q16740 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22966518 | 0.85 | SMN1; SMN2 (0.47) | SMN1; SMN2POLBSIGMAR1CLPPALDH1A1 | |
| SCHEMBL12680943 | 0.83 | RAB9A (0.60) | SMN1; SMN2ALDH1A1RAB9AKMT2AGAA | |
| SCHEMBL22966556 | 0.75 | PDCD1 (0.52) | SMN1; SMN2ALDH1A1RAB9AKMT2AGAA | |
| SCHEMBL6369558 | 0.72 | RAD52 (0.69) | SMN1; SMN2POLBALDH1A1RAB9AKMT2A | |
| SCHEMBL13476804 | 0.71 | SIGMAR1 (0.49) | SMN1; SMN2POLBSIGMAR1CLPPRAB9A | |
| SCHEMBL10620235 | 0.70 | SIGMAR1 (0.61) | SMN1; SMN2POLBSIGMAR1ALDH1A1KMT2A | |
| SCHEMBL12680942 | 0.70 | RAD52 (0.53) | POLBALDH1A1KMT2AGAAMEN1 | |
| Hydrochloric Acid SCHEMBL11704598 | 0.69 | SMN1; SMN2 (0.62) | SMN1; SMN2POLBSIGMAR1ALDH1A1RAB9A | |
| SCHEMBL16286091 | 0.69 | RAD52 (0.48) | SMN1; SMN2POLBALDH1A1RAB9AKMT2A | |
| SCHEMBL17088067 | 0.69 | RAD52 (0.48) | SMN1; SMN2POLBALDH1A1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019192506-A1 | IMMUNOMODULATORS, COMPOSITIONS AND METHODS THEREOF | BETTA PHARMACEUTICALS CO., LTD (CN) | 2019-10-10 | — | — | WO | disclosed |