⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2755715 | 0.81 | — | — | |
| SCHEMBL21500948 | 0.76 | L3MBTL1 (0.33) | — | |
| SCHEMBL25923907 | 0.72 | — | — | |
| SCHEMBL25587182 | 0.69 | — | — | |
| SCHEMBL26275972 | 0.69 | GAA (0.36) | — | |
| SCHEMBL19225717 | 0.69 | — | — | |
| SCHEMBL26275291 | 0.69 | GAA (0.33) | — | |
| SCHEMBL802249 | 0.69 | GAA (0.39) | — | |
| SCHEMBL26738545 | 0.69 | GAA (0.33) | — | |
| SCHEMBL25587175 | 0.69 | ADORA2A (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10918645-B2 | Substituted tricyclic heterocyclic compounds and use thereof | LIFEARC (GB) | 2021-02-16 | — | — | US | disclosed |
| US-20190307763-A1 | SUBSTITUTED TRICYCLIC HETEROCYCLIC COMPOUNDS AND USE THEREOF | LIFEARC (GB) | 2019-10-10 | — | — | US | disclosed |