Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | GSR | P00390 | 2/20 | 0.32 |
| ▸ | TYMP | P19971 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10862575 | 0.81 | OGA (0.44) | OGASMN1; SMN2NPC1RAB9ATRPM5 | |
| SCHEMBL2258773 | 0.78 | OGA (0.40) | OGASMN1; SMN2NPC1RAB9ATRPM5 | |
| SCHEMBL22966747 | 0.77 | GSR (0.39) | SMN1; SMN2NPC1RAB9AGSRMAPT | |
| SCHEMBL16373614 | 0.73 | — | — | |
| SCHEMBL4324910 | 0.72 | — | — | |
| SCHEMBL6936153 | 0.71 | MME (0.48) | OGASMN1; SMN2NPC1RAB9ATRPM5 | |
| SCHEMBL13398310 | 0.69 | SMN1; SMN2 (0.40) | SMN1; SMN2NPC1RAB9AALDH1A1POLB | |
| SCHEMBL4771732 | 0.69 | MME (0.44) | OGASMN1; SMN2NPC1RAB9ATRPM5 | |
| SCHEMBL17788454 | 0.68 | TRPM5 (0.38) | OGASMN1; SMN2NPC1RAB9ATRPM5 | |
| SCHEMBL16366959 | 0.68 | TP53 (0.47) | SMN1; SMN2NPC1RAB9ATP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019192506-A1 | IMMUNOMODULATORS, COMPOSITIONS AND METHODS THEREOF | BETTA PHARMACEUTICALS CO., LTD (CN) | 2019-10-10 | — | — | WO | disclosed |