Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.31 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.31 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21104411 | 0.87 | NCF1 (0.33) | NCF1CARM1PRMT6 | |
| SCHEMBL8504951 | 0.78 | — | — | |
| SCHEMBL13576372 | 0.77 | NCF1 (0.32) | NCF1 | |
| SCHEMBL13713091 | 0.77 | NCF1 (0.32) | NCF1 | |
| SCHEMBL7513512 | 0.76 | — | — | |
| SCHEMBL27848369 | 0.74 | — | — | |
| SCHEMBL21592510 | 0.74 | — | — | |
| SCHEMBL16442182 | 0.73 | NCF1 (0.34) | NCF1KMT2A | |
| SCHEMBL13244668 | 0.73 | SLC6A2 (0.34) | KMT2A | |
| SCHEMBL20041861 | 0.72 | NCF1 (0.32) | NCF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019193516-A2 | SUBSTITUTED PYRIDINE AND PYRIMIDINES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2019-10-10 | — | — | WO | disclosed |