Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.34 |
| ▸ | SHBG | P04278 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14432000 | 0.80 | — | — | |
| SCHEMBL10238598 | 0.78 | SMN1; SMN2 (0.32) | SHBG | |
| SCHEMBL10188211 | 0.76 | — | — | |
| SCHEMBL11915409 | 0.75 | — | — | |
| SCHEMBL27663102 | 0.75 | — | — | |
| SCHEMBL13576372 | 0.75 | NCF1 (0.32) | NCF1 | |
| SCHEMBL13713091 | 0.75 | NCF1 (0.32) | NCF1 | |
| SCHEMBL21452801 | 0.73 | NCF1 (0.31) | NCF1KMT2A | |
| SCHEMBL1870619 | 0.73 | SHBG (0.50) | SHBG | |
| SCHEMBL170904 | 0.73 | SHBG (0.50) | SHBG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8946422-B2 | 8-methoxy-9H-isothiazolo[5,4-B]quinoline-3,4-diones and related compounds as anti-infective agents | ACHILLION PHARMACEUTICALS, INC. (US) | 2015-02-03 | — | — | US | disclosed |