Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TLR4 | O00206 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.42 |
| ▸ | FASN | P49327 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13866437 | 1.00 | ATM (0.50) | ATMALDH1A1KDM4ETLR4MTNR1A | |
| SCHEMBL14922428 | 0.91 | ALDH1A1 (0.53) | ATMALDH1A1KDM4ETLR4MTNR1A | |
| SCHEMBL18502884 | 0.91 | ALDH1A1 (0.53) | ATMALDH1A1KDM4ETLR4MTNR1A | |
| SCHEMBL23352154 | 0.90 | ATM (0.46) | ATMALDH1A1KDM4ETLR4MTNR1A | |
| SCHEMBL10245502 | 0.86 | ATM (0.48) | ATMALDH1A1KDM4ETLR4MTNR1A | |
| SCHEMBL20912045 | 0.86 | ATM (0.54) | ATMALDH1A1KDM4ETLR4MTNR1A | |
| SCHEMBL21452802 | 0.86 | ATM (0.48) | ATMALDH1A1KDM4ETLR4MTNR1A | |
| SCHEMBL17780153 | 0.86 | ATM (0.54) | ATMALDH1A1KDM4ETLR4MTNR1A | |
| SCHEMBL21452879 | 0.86 | ATM (0.54) | ATMALDH1A1KDM4ETLR4MTNR1A | |
| SCHEMBL15765690 | 0.86 | ATM (0.48) | ATMALDH1A1KDM4ETLR4MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019193516-A2 | SUBSTITUTED PYRIDINE AND PYRIMIDINES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2019-10-10 | — | — | WO | disclosed |