Sugi Predict

Sugi Predict / Compounds / SCHEMBL10245502

SCHEMBL10245502

SCHEMBL10245502

CNC1CCC(NC(C)=O)CC1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ATM Q13315 1/20 0.48
▸ ALDH1A1 P00352 3/20 0.45
▸ KDM4E B2RXH2 2/20 0.45
▸ EPHX2 P34913 2/20 0.41
▸ MTNR1A P48039 1/20 0.40
▸ MTNR1B P49286 1/20 0.40
▸ MMP2 P08253 1/20 0.39
▸ MMP8 P22894 1/20 0.39
▸ EPHX1 P07099 6/20 0.39
▸ KDM1A O60341 1/20 0.37
▸ NPC1 O15118 2/20 0.37
▸ RAB9A P51151 2/20 0.37
▸ SMN1; SMN2 Q16637 2/20 0.37
▸ MAPT P10636 1/20 0.37
▸ CYP3A4 P08684 1/20 0.37
▸ CA1 P00915 2/20 0.37
▸ CA2 P00918 2/20 0.37
▸ TLR4 O00206 1/20 0.37
▸ CA12 O43570 1/20 0.37
▸ CA9 Q16790 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21452802 1.00 ATM (0.48) ATMALDH1A1KDM4EEPHX2MTNR1A
SCHEMBL15765690 1.00 ATM (0.48) ATMALDH1A1KDM4EEPHX2MTNR1A
SCHEMBL284319 0.89 ATM (0.56) ATMALDH1A1KDM4EEPHX2MTNR1A
SCHEMBL284318 0.89 ATM (0.56) ATMALDH1A1KDM4EEPHX2MTNR1A
SCHEMBL50350 0.89 — —
SCHEMBL284342 0.89 ATM (0.56) ATMALDH1A1KDM4EEPHX2MTNR1A
Hydrochloric Acid SCHEMBL27752288 0.87 — —
Water SCHEMBL27364290 0.87 — —
SCHEMBL21452830 0.86 ATM (0.50) ATMALDH1A1KDM4EEPHX2MTNR1A
SCHEMBL13866437 0.86 ATM (0.50) ATMALDH1A1KDM4EEPHX2MTNR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11914248-B2 Photo-alignment copolymer, photo-alignment film, and optical laminate FUJIFILM CORPORATION (JP) 2024-02-27 — — US disclosed
US-20230217789-A1 OPTICAL LAMINATE AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-07-06 — — US disclosed
US-20230213695-A1 LAMINATES, POLARIZING PLATES, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-07-06 — — US disclosed
US-20230217789-A1 OPTICAL LAMINATE AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-07-06 — — US disclosed
US-11692050-B2 Photo-alignment copolymer, binder composition, binder layer, optical laminate, and image display device FUJIFILM CORPORATION (JP) 2023-07-04 — — US disclosed
WO-2022218379-A1 SMALL-MOLECULE COMPOUND HAVING SUBSTITUTED PHENYL SPIRO[INDOLINE-3,3'-PYRROLIDINE] STRUCTURE 中国科学院上海药物研究所 2022-10-20 — — WO disclosed
EP-3825313-A1 PYRIDIN-2(1H)-ONE DERIVATIVES AS BROMODOMAIN INHIBITORS AbbVie Inc. (US) 2021-05-26 — — EP disclosed
US-20210047304-A1 Bromodomain Inhibitors ABBVIE INC. 2021-02-18 — — US disclosed
US-20170327509-A1 TWO-PHOTON ABSORBING FLUOROPHORES AND METHOD FOR CELLULAR IMAGING USING THE SAME POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) 2017-11-16 — — US disclosed
US-9790221-B2 Heteroaryl compounds as IRAK inhibitors and uses thereof MERCK PATENT GMBH (DE) 2017-10-17 — — US disclosed
US-20080119457-A1 Benzene, Pyridine, and Pyridazine Derivatives SERENEX, INC. 2008-05-22 — — US disclosed
US-20080119457-A1 Benzene, Pyridine, and Pyridazine Derivatives SERENEX, INC. 2008-05-22 — — US disclosed
US-20080076800-A1 Benzene, Pyridine, and Pyridazine Derivatives SERENEX, INC. 2008-03-27 — — US disclosed
US-20080076813-A1 Benzene, Pyridine, and Pyridazine Derivatives SERENEX, INC. 2008-03-27 — — US disclosed
US-20080076813-A1 Benzene, Pyridine, and Pyridazine Derivatives SERENEX, INC. 2008-03-27 — — US disclosed
US-20080076800-A1 Benzene, Pyridine, and Pyridazine Derivatives SERENEX, INC. 2008-03-27 — — US disclosed
US-20080070918-A1 Dihydropyridazine, Tetrahydropyridine, Chromanone, and Dihydronaphthalenone Derivatives SERENEX, INC. 2008-03-20 — — US disclosed
US-20080070918-A1 Dihydropyridazine, Tetrahydropyridine, Chromanone, and Dihydronaphthalenone Derivatives SERENEX, INC. 2008-03-20 — — US disclosed
US-20080070930-A1 Pyrimidine and Pyrazine Derivatives SERENEX, INC. 2008-03-20 — — US disclosed
US-20080070930-A1 Pyrimidine and Pyrazine Derivatives SERENEX, INC. 2008-03-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210047304-A1 Bromodomain Inhibitors BRD4, BRD1, BRD3 ATM 1363/4885ALDH1A1 2378/4885KDM4E 683/4885
US-20080070930-A1 Pyrimidine and Pyrazine Derivatives P2RX7, P2RX5, P2RX3 ATM 2064/4885ALDH1A1 986/4885KDM4E 2902/4885
US-20080070918-A1 Dihydropyridazine, Tetrahydropyridine, Chromanone, and Dihydronaphthalenone Derivatives QDPR, CCND2, CCND1 ATM 2747/4885ALDH1A1 143/4885KDM4E 1793/4885
US-20080076800-A1 Benzene, Pyridine, and Pyridazine Derivatives RB1, MKI67, CCNB1 ATM 2009/4885ALDH1A1 767/4885KDM4E 1246/4885
US-20170327509-A1 TWO-PHOTON ABSORBING FLUOROPHORES AND METHOD FOR CELLULAR IMAGING USING THE SAME ACE2, DNPEP, ACE ATM 2836/4885ALDH1A1 298/4885KDM4E 3999/4885
US-20080076813-A1 Benzene, Pyridine, and Pyridazine Derivatives MKI67, CCNB1, CCNB3 ATM 2116/4885ALDH1A1 580/4885KDM4E 1162/4885
US-20080119457-A1 Benzene, Pyridine, and Pyridazine Derivatives MKI67, CCNB1, RB1 ATM 2317/4885ALDH1A1 440/4885KDM4E 1597/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.