Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | DCK | P27707 | 2/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | ITGB2 | P05107 | 3/20 | 0.30 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.30 |
| ▸ | ITGAL | P20701 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21452764 | 0.71 | RPS6KB1 (0.45) | CYP1A2CYP2C19ITGB2ICAM1ITGAL | |
| SCHEMBL21452930 | 0.66 | LRRK2 (0.35) | CYP1A2CYP2C19LRRK2ITGB2ICAM1 | |
| SCHEMBL21452765 | 0.65 | ITGB2 (0.40) | CYP1A2ITGB2ICAM1ITGAL | |
| SCHEMBL21452845 | 0.65 | PDE3B (0.41) | CYP1A2CYP2C19ITGB2ICAM1ITGAL | |
| SCHEMBL31614476 | 0.64 | OGA (0.38) | CYP1A2CYP2C19 | |
| SCHEMBL31383394 | 0.64 | CYP2C19 (0.58) | CYP2C19DCK | |
| SCHEMBL21434031 | 0.63 | ITGB2 (0.55) | FFAR4ITGB2ICAM1ITGAL | |
| SCHEMBL31038211 | 0.63 | LRRK2 (0.46) | CYP1A2CYP2C19LRRK2 | |
| SCHEMBL15006808 | 0.61 | ACACB (0.42) | FFAR4CYP1A2CYP2C19ACACBITGB2 | |
| SCHEMBL25818930 | 0.60 | CTSS (0.35) | FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019193516-A2 | SUBSTITUTED PYRIDINE AND PYRIMIDINES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2019-10-10 | — | — | WO | disclosed |