Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | AQP1 | P29972 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.36 |
| ▸ | LTA4H | P09960 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22922701 | 0.78 | HPGD (0.49) | ALDH1A1NPSR1LMNAKDM4EUSP2 | |
| SCHEMBL21436379 | 0.77 | KDM4E (0.51) | ALDH1A1NPSR1LMNAKDM4EUSP2 | |
| SCHEMBL22922705 | 0.75 | CA2 (0.54) | ALDH1A1NPSR1LMNAKDM4EUSP2 | |
| SCHEMBL21453448 | 0.75 | ALDH1A1 (0.42) | ALDH1A1NPSR1LMNAKDM4EUSP2 | |
| SCHEMBL22922704 | 0.69 | HPGD (0.41) | ALDH1A1NPSR1LMNAKDM4EUSP2 | |
| SCHEMBL21436493 | 0.69 | HPGD (0.41) | ALDH1A1NPSR1LMNAKDM4EUSP2 | |
| SCHEMBL21436494 | 0.69 | HPGD (0.41) | ALDH1A1NPSR1LMNAKDM4EUSP2 | |
| SCHEMBL21019020 | 0.65 | KDM4E (0.72) | ALDH1A1NPSR1LMNAKDM4EUSP2 | |
| SCHEMBL9836580 | 0.64 | ALDH1A1 (0.53) | ALDH1A1NPSR1LMNAKDM4EUSP2 | |
| SCHEMBL2741861 | 0.64 | KDM4E (0.72) | ALDH1A1NPSR1LMNAKDM4EUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019193159-A1 | BUMETANIDE DERIVATIVES FOR THE THERAPY OF HYPERHIDROSIS | Universität Wien (AT) | 2019-10-10 | — | — | WO | disclosed |
| US-20160184465-A1 | METHOD FOR PRODUCTION OF F-18 LABELED AMYLOID BETA LIGANDS | PIRAMAL IMAGING SA (CH) | 2016-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160184465-A1 | METHOD FOR PRODUCTION OF F-18 LABELED AMYLOID BETA LIGANDS | APP, APBA1, BACE1 | ALDH1A1 3739/4885NPSR1 490/4885LMNA 2057/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.