SCHEMBL21453477

SCHEMBL21453477

c1ccc2c(c1)sc1c2ccc2c3cccc4c5ccccc5c5ccccc5c5ccccc5n(c43)c21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.41
MAPT P10636 4/20 0.38
HPGD P15428 3/20 0.38
ALDH1A1 P00352 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
KDM4E B2RXH2 2/20 0.38
POLB P06746 1/20 0.38
HTT P42858 1/20 0.38
ALOX5 P09917 1/20 0.37
RAB9A P51151 3/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
PARP14 Q460N5 1/20 0.35
ALKBH5 Q6P6C2 1/20 0.34
FTO Q9C0B1 1/20 0.34
RXFP1 Q9HBX9 1/20 0.32
PRKDC P78527 1/20 0.32
TP53 P04637 2/20 0.32
ESR2 Q92731 1/20 0.31
TNKS O95271 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19890696 0.98 GPR3 (0.42) GPR3MAPTHPGDALDH1A1MEN1
SCHEMBL21454079 0.91 GPR3 (0.40) GPR3MAPTHPGDALDH1A1MEN1
SCHEMBL19563760 0.88 GPR3 (0.48) GPR3MAPTHPGDALDH1A1MEN1
SCHEMBL21453523 0.87 GPR3 (0.37) GPR3MAPTHPGDALDH1A1MEN1
SCHEMBL21454061 0.87 GPR3 (0.39) GPR3MAPTHPGDALDH1A1ALOX5
SCHEMBL21453480 0.85 GPR3 (0.36) GPR3MAPTHPGDALDH1A1MEN1
SCHEMBL21473043 0.82 PARP14 (0.40) GPR3MAPTHPGDALDH1A1MEN1
SCHEMBL17995044 0.81 MAPT (0.36) GPR3MAPTHPGDALDH1A1MEN1
SCHEMBL24442111 0.79 GPR3 (0.35) GPR3MAPTHPGDALDH1A1MEN1
SCHEMBL21453478 0.79 GPR3 (0.39) GPR3MAPTHPGDALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11038121-B2 9 membered ring carbazole compounds Beijing Summer Sprout Technology Co., Ltd. (CN) 2021-06-15 US disclosed
US-20190312214-A1 9 MEMBERED RING CARBAZOLE COMPOUNDS BEIJING SUMMER SPROUT TECHNOLOGY CO., LTD (CN) 2019-10-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11038121-B2 9 membered ring carbazole compounds SLC25A21, OCIAD2, OXA1L GPR3 478/4885MAPT 2041/4885HPGD 830/4885
US-20190312214-A1 9 MEMBERED RING CARBAZOLE COMPOUNDS SLC25A21, OCIAD2, OXA1L GPR3 478/4885MAPT 2041/4885HPGD 830/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.